Rrp2, a σ 54-dependent transcriptional activator of Borrelia burgdorferi, activates rpoS in an enhancer-independent manner

Jon S. Blevins, Haijun Xu, Ming He, Michael V. Norgard, Larry Reitzer, X. Frank Yang

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Rrp2 is the sole σ 54-dependent transcriptional activator present in the Borrelia burgdorferi genome. We showed that recombinant Rrp2 binds to DNA in a sequence-nonspecific manner. During infection, Rrp2 activates σ 54-dependent rpoS expression without an apparent upstream enhancer element commonly associated with other σ 54-dependent transcriptional activators.

Original languageEnglish (US)
Pages (from-to)2902-2905
Number of pages4
JournalJournal of Bacteriology
Volume191
Issue number8
DOIs
StatePublished - Apr 2009

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Borrelia burgdorferi
Genome
DNA
Infection

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

Cite this

Rrp2, a σ 54-dependent transcriptional activator of Borrelia burgdorferi, activates rpoS in an enhancer-independent manner. / Blevins, Jon S.; Xu, Haijun; He, Ming; Norgard, Michael V.; Reitzer, Larry; Yang, X. Frank.

In: Journal of Bacteriology, Vol. 191, No. 8, 04.2009, p. 2902-2905.

Research output: Contribution to journalArticle

Blevins, Jon S. ; Xu, Haijun ; He, Ming ; Norgard, Michael V. ; Reitzer, Larry ; Yang, X. Frank. / Rrp2, a σ 54-dependent transcriptional activator of Borrelia burgdorferi, activates rpoS in an enhancer-independent manner. In: Journal of Bacteriology. 2009 ; Vol. 191, No. 8. pp. 2902-2905.
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