Purpose: To report two cases of iris neovascularization associated with systemic cryoglobulinemia. Design: Retrospective case report. Methods: Patient chart review and review of literature. Results: Two patients with iris neovascularization in the absence of retinal ischemia were subsequently found to have systemic cryoglobulinemia. Successful treatment of one patient's underlying lymphoma led to stabilization and resolution of neovascularization. Conclusions: Systemic cryoglobulinemia may be associated with anterior segment ischemia and neovascularization, and should be considered in the differential diagnosis of iris neovascularization in the absence of apparent retinal ischemia.
ASJC Scopus subject areas