Rupture of intracranial aneurysms during endovascular coiling: Management and outcomes

Elad Levy, Christopher J. Koebbe, Michael B. Horowitz, Charles A. Jungreis, G. Lee Pride, Kim Dutton, Amin Kassam, Phillip D. Purdy

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

OBJECTIVE: In this study, the incidence, etiologies, and management with respect to clinical outcome of patients with iatrogenic aneurysmal rupture during attempted coil embolization of intracranial aneurysms are reviewed. METHODS: A retrospective analysis was conducted of 274 patients with intracranial aneurysms treated with Guglielmi detachable coils over a 6-year period from 1994 to 2000. Patient medical records were examined for demographic data, aneurysm location, the number of coils deployed preceding and after aneurysmal rupture, the etiology of the rupture, and the clinical status on admission and at the time of discharge. RESULTS: Of 274 patients with intracranial aneurysms treated with coil embolization, six (2%) had an intraprocedural rupture. Of these six, two were women and four were men. The mean age was 67 years (range, 52-85 yr). Mean follow-up time was 8 months (range, 0-25 mo). Aneurysmal rupture resulted from detachment of the last coil in three patients, detachment of the third coil (of four) in one patient, and insertion of the first coil in another patient. In one patient, the aneurysmal rupture was a result of catheter advancement before detachment of the last coil. The Glasgow Outcome Scale score at last follow-up examination was 1 in two patients, 2 in two patients, and 5 in two patients. CONCLUSION: The rate of rupture of aneurysms during coil embolization is approximately 2 to 4%. The clinical outcome may be related to the timing of the rupture and the number of coils placed before rupture. If extravasation of contrast agent is seen, which suggests intraprocedural rupture, further coil deposition should be attempted if safely possible.

Original languageEnglish (US)
Pages (from-to)807-813
Number of pages7
JournalNeurosurgery
Volume49
Issue number4
StatePublished - 2001

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Intracranial Aneurysm
Rupture
Aneurysm
Glasgow Outcome Scale
Contrast Media
Medical Records
Cohort Studies
Catheters
Demography

Keywords

  • Aneurysm
  • Coil embolization
  • Endovascular
  • Guglielmi detachable coils

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Levy, E., Koebbe, C. J., Horowitz, M. B., Jungreis, C. A., Pride, G. L., Dutton, K., ... Purdy, P. D. (2001). Rupture of intracranial aneurysms during endovascular coiling: Management and outcomes. Neurosurgery, 49(4), 807-813.

Rupture of intracranial aneurysms during endovascular coiling : Management and outcomes. / Levy, Elad; Koebbe, Christopher J.; Horowitz, Michael B.; Jungreis, Charles A.; Pride, G. Lee; Dutton, Kim; Kassam, Amin; Purdy, Phillip D.

In: Neurosurgery, Vol. 49, No. 4, 2001, p. 807-813.

Research output: Contribution to journalArticle

Levy, E, Koebbe, CJ, Horowitz, MB, Jungreis, CA, Pride, GL, Dutton, K, Kassam, A & Purdy, PD 2001, 'Rupture of intracranial aneurysms during endovascular coiling: Management and outcomes', Neurosurgery, vol. 49, no. 4, pp. 807-813.
Levy E, Koebbe CJ, Horowitz MB, Jungreis CA, Pride GL, Dutton K et al. Rupture of intracranial aneurysms during endovascular coiling: Management and outcomes. Neurosurgery. 2001;49(4):807-813.
Levy, Elad ; Koebbe, Christopher J. ; Horowitz, Michael B. ; Jungreis, Charles A. ; Pride, G. Lee ; Dutton, Kim ; Kassam, Amin ; Purdy, Phillip D. / Rupture of intracranial aneurysms during endovascular coiling : Management and outcomes. In: Neurosurgery. 2001 ; Vol. 49, No. 4. pp. 807-813.
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AU - Pride, G. Lee

AU - Dutton, Kim

AU - Kassam, Amin

AU - Purdy, Phillip D.

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N2 - OBJECTIVE: In this study, the incidence, etiologies, and management with respect to clinical outcome of patients with iatrogenic aneurysmal rupture during attempted coil embolization of intracranial aneurysms are reviewed. METHODS: A retrospective analysis was conducted of 274 patients with intracranial aneurysms treated with Guglielmi detachable coils over a 6-year period from 1994 to 2000. Patient medical records were examined for demographic data, aneurysm location, the number of coils deployed preceding and after aneurysmal rupture, the etiology of the rupture, and the clinical status on admission and at the time of discharge. RESULTS: Of 274 patients with intracranial aneurysms treated with coil embolization, six (2%) had an intraprocedural rupture. Of these six, two were women and four were men. The mean age was 67 years (range, 52-85 yr). Mean follow-up time was 8 months (range, 0-25 mo). Aneurysmal rupture resulted from detachment of the last coil in three patients, detachment of the third coil (of four) in one patient, and insertion of the first coil in another patient. In one patient, the aneurysmal rupture was a result of catheter advancement before detachment of the last coil. The Glasgow Outcome Scale score at last follow-up examination was 1 in two patients, 2 in two patients, and 5 in two patients. CONCLUSION: The rate of rupture of aneurysms during coil embolization is approximately 2 to 4%. The clinical outcome may be related to the timing of the rupture and the number of coils placed before rupture. If extravasation of contrast agent is seen, which suggests intraprocedural rupture, further coil deposition should be attempted if safely possible.

AB - OBJECTIVE: In this study, the incidence, etiologies, and management with respect to clinical outcome of patients with iatrogenic aneurysmal rupture during attempted coil embolization of intracranial aneurysms are reviewed. METHODS: A retrospective analysis was conducted of 274 patients with intracranial aneurysms treated with Guglielmi detachable coils over a 6-year period from 1994 to 2000. Patient medical records were examined for demographic data, aneurysm location, the number of coils deployed preceding and after aneurysmal rupture, the etiology of the rupture, and the clinical status on admission and at the time of discharge. RESULTS: Of 274 patients with intracranial aneurysms treated with coil embolization, six (2%) had an intraprocedural rupture. Of these six, two were women and four were men. The mean age was 67 years (range, 52-85 yr). Mean follow-up time was 8 months (range, 0-25 mo). Aneurysmal rupture resulted from detachment of the last coil in three patients, detachment of the third coil (of four) in one patient, and insertion of the first coil in another patient. In one patient, the aneurysmal rupture was a result of catheter advancement before detachment of the last coil. The Glasgow Outcome Scale score at last follow-up examination was 1 in two patients, 2 in two patients, and 5 in two patients. CONCLUSION: The rate of rupture of aneurysms during coil embolization is approximately 2 to 4%. The clinical outcome may be related to the timing of the rupture and the number of coils placed before rupture. If extravasation of contrast agent is seen, which suggests intraprocedural rupture, further coil deposition should be attempted if safely possible.

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