Safety and efficacy of rocuronium for controlled intubation with paralytics in the pediatric emergency department

D. R. Mendez, C. S. Goto, T. J. Abramo, R. A. Wiebe

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Controlled intubation in the pediatric emergency department (ED) requires a paralytic agent that is safe, efficacious, and of rapid onset. The safety of succinylcholine has been challenged, leading some clinicians to use vecuronium as an alternative. Rocuronium's onset is similar to that of succinylcholine. Objective: To evaluate the safety and efficacy of rocuronium for controlled intubation with paralysis (CIP) in the pediatric ED. Methods: A retrospective, observational study reviewed the records of patients less than 15 years of age, who received controlled intubation with paralytics at two Dallas EDs. The patients received either vecuronium or rocuronium. Results: The study included 84 patients (vecuronium 19, rocuronium 65). Complications were similar between the two groups. Rocuronium had a shorter time from administration to intubation when compared to vecuronium (P < 0.05). Conclusion: Rocuronium is as safe and efficacious as vecuronium for CIP in the pediatric ED.

Original languageEnglish (US)
Pages (from-to)233-236
Number of pages4
JournalPediatric Emergency Care
Volume17
Issue number4
DOIs
StatePublished - 2001

Fingerprint

Vecuronium Bromide
Intubation
Hospital Emergency Service
Pediatrics
Safety
Succinylcholine
Paralysis
Observational Studies
rocuronium
Retrospective Studies

Keywords

  • Aspiration
  • Bradycardia
  • Hypotension
  • Hypoxia
  • Rocuronium
  • Tracheal intubation
  • Vecuronium

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nursing(all)
  • Emergency Medicine

Cite this

Safety and efficacy of rocuronium for controlled intubation with paralytics in the pediatric emergency department. / Mendez, D. R.; Goto, C. S.; Abramo, T. J.; Wiebe, R. A.

In: Pediatric Emergency Care, Vol. 17, No. 4, 2001, p. 233-236.

Research output: Contribution to journalArticle

Mendez, D. R. ; Goto, C. S. ; Abramo, T. J. ; Wiebe, R. A. / Safety and efficacy of rocuronium for controlled intubation with paralytics in the pediatric emergency department. In: Pediatric Emergency Care. 2001 ; Vol. 17, No. 4. pp. 233-236.
@article{763c5e80b5af4111a45b27f3487a4a9f,
title = "Safety and efficacy of rocuronium for controlled intubation with paralytics in the pediatric emergency department",
abstract = "Background: Controlled intubation in the pediatric emergency department (ED) requires a paralytic agent that is safe, efficacious, and of rapid onset. The safety of succinylcholine has been challenged, leading some clinicians to use vecuronium as an alternative. Rocuronium's onset is similar to that of succinylcholine. Objective: To evaluate the safety and efficacy of rocuronium for controlled intubation with paralysis (CIP) in the pediatric ED. Methods: A retrospective, observational study reviewed the records of patients less than 15 years of age, who received controlled intubation with paralytics at two Dallas EDs. The patients received either vecuronium or rocuronium. Results: The study included 84 patients (vecuronium 19, rocuronium 65). Complications were similar between the two groups. Rocuronium had a shorter time from administration to intubation when compared to vecuronium (P < 0.05). Conclusion: Rocuronium is as safe and efficacious as vecuronium for CIP in the pediatric ED.",
keywords = "Aspiration, Bradycardia, Hypotension, Hypoxia, Rocuronium, Tracheal intubation, Vecuronium",
author = "Mendez, {D. R.} and Goto, {C. S.} and Abramo, {T. J.} and Wiebe, {R. A.}",
year = "2001",
doi = "10.1097/00006565-200108000-00001",
language = "English (US)",
volume = "17",
pages = "233--236",
journal = "Pediatric Emergency Care",
issn = "0749-5161",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Safety and efficacy of rocuronium for controlled intubation with paralytics in the pediatric emergency department

AU - Mendez, D. R.

AU - Goto, C. S.

AU - Abramo, T. J.

AU - Wiebe, R. A.

PY - 2001

Y1 - 2001

N2 - Background: Controlled intubation in the pediatric emergency department (ED) requires a paralytic agent that is safe, efficacious, and of rapid onset. The safety of succinylcholine has been challenged, leading some clinicians to use vecuronium as an alternative. Rocuronium's onset is similar to that of succinylcholine. Objective: To evaluate the safety and efficacy of rocuronium for controlled intubation with paralysis (CIP) in the pediatric ED. Methods: A retrospective, observational study reviewed the records of patients less than 15 years of age, who received controlled intubation with paralytics at two Dallas EDs. The patients received either vecuronium or rocuronium. Results: The study included 84 patients (vecuronium 19, rocuronium 65). Complications were similar between the two groups. Rocuronium had a shorter time from administration to intubation when compared to vecuronium (P < 0.05). Conclusion: Rocuronium is as safe and efficacious as vecuronium for CIP in the pediatric ED.

AB - Background: Controlled intubation in the pediatric emergency department (ED) requires a paralytic agent that is safe, efficacious, and of rapid onset. The safety of succinylcholine has been challenged, leading some clinicians to use vecuronium as an alternative. Rocuronium's onset is similar to that of succinylcholine. Objective: To evaluate the safety and efficacy of rocuronium for controlled intubation with paralysis (CIP) in the pediatric ED. Methods: A retrospective, observational study reviewed the records of patients less than 15 years of age, who received controlled intubation with paralytics at two Dallas EDs. The patients received either vecuronium or rocuronium. Results: The study included 84 patients (vecuronium 19, rocuronium 65). Complications were similar between the two groups. Rocuronium had a shorter time from administration to intubation when compared to vecuronium (P < 0.05). Conclusion: Rocuronium is as safe and efficacious as vecuronium for CIP in the pediatric ED.

KW - Aspiration

KW - Bradycardia

KW - Hypotension

KW - Hypoxia

KW - Rocuronium

KW - Tracheal intubation

KW - Vecuronium

UR - http://www.scopus.com/inward/record.url?scp=0034857106&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034857106&partnerID=8YFLogxK

U2 - 10.1097/00006565-200108000-00001

DO - 10.1097/00006565-200108000-00001

M3 - Article

C2 - 11493818

AN - SCOPUS:0034857106

VL - 17

SP - 233

EP - 236

JO - Pediatric Emergency Care

JF - Pediatric Emergency Care

SN - 0749-5161

IS - 4

ER -