IN THE CURRENT RADIATION therapy practice, treatment plans are generated based on a snapshot of the patient’s anatomy captured during treatment simulation and then delivered fractionally over a number of weeks. However, the patient’s anatomy may vary significantly from fraction to fraction. These variations occur when a patient loses weight, when the tumor regresses during therapy [1-3], when organs such as bladder and rectum have different filling status , etc. With the advent of onboard cone-beam computed tomography (CBCT), interfraction geometry variations can be readily measured before each treatment fraction and the static radiation therapy process can potentially be transformed into a dynamic one, that is, online adaptive radiation therapy (ART) [5,6].
ASJC Scopus subject areas
- Physics and Astronomy(all)