Screening recipients of increased risk donor organs: A multicenter retrospective study

Michael G. Ison, Meenakshi M. Rana, Kyle D. Brizendine, Sonia Chimienti, Jade Le, Rosette Kfoury, Parvin Mohazabnia, Nicole Theodoropoulos

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Organ Procurement & Transplantation Network policy requires post-transplant screening of recipients of organs from donors at increased risk for transmission of HIV, hepatitis B virus, and hepatitis C virus. Available data suggest that follow-up testing of recipients is not routinely conducted. Data on increased risk donors and recipients of their organs from 2008 to 2012 were retrospectively collected from 6 transplant centers after IRB approval. Descriptive statistics were performed. About 363 (60%) recipients were screened for transmission of HIV, HBV, and/or HCV at some time point; 257 (70.8%) within 90 days of transplant. The type of test used to screen for infection was variable with many recipients (25%-43%) screened with serology alone. Our results reveal that post-transplant screening for HIV, HBV, and HCV in recipients of increased risk donor organs did not universally occur and testing methods were variable.

Original languageEnglish (US)
Article numbere12862
JournalTransplant Infectious Disease
Volume20
Issue number3
DOIs
StatePublished - Jun 1 2018

Keywords

  • hepatitis B
  • hepatitis C
  • HIV
  • organ recipients
  • PHS increased risk donors
  • screening

ASJC Scopus subject areas

  • Transplantation
  • Infectious Diseases

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    Ison, M. G., Rana, M. M., Brizendine, K. D., Chimienti, S., Le, J., Kfoury, R., Mohazabnia, P., & Theodoropoulos, N. (2018). Screening recipients of increased risk donor organs: A multicenter retrospective study. Transplant Infectious Disease, 20(3), [e12862]. https://doi.org/10.1111/tid.12862