Second-generation cyclooxygenase-2-specific inhibitors

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Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective as anti-inflammatory agents, analgesics, and antipyretics. Their widespread use is in large part attributable to the high prevalence of osteoarthritis and other painful musculoskeletal conditions. These compounds, however, are associated with a broad spectrum of untoward reactions, especially in the gastrointestinal (GI) tract and kidney, and problems of platelet function.

Original languageEnglish (US)
Pages (from-to)122-128
Number of pages7
JournalClinical Perspectives in Gastroenterology
Volume5
Issue number2
Publication statusPublished - 2002

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ASJC Scopus subject areas

  • Gastroenterology

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