Secretory proteins in the perfused human placenta

J. Dancis; N. K. Ghosh; V. Jansen; H. Schneider; R. J. Fallon; R. P. Cox

doi:10.1159/000241171

Secretory proteins in the perfused human placenta

J. Dancis, N. K. Ghosh, V. Jansen, H. Schneider, R. J. Fallon, R. P. Cox

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4 Scopus citations

Abstract

A relatively simple perfusion technique of human placenta has been applied to the study of secretory proteins. Preferential secretion into the maternal circulation of human chorionic gonadotropin (HCG), human chorionic somatomammotropin (HCS), follicle-stimulating hormone (FSH), and placental alkaline phosphatase has been demonstrated, contrasting with the bidirectional secretion of progesterone. Evidence is presented for the net synthesis of HCS during perfusion. The technique offers advantages in the study of synthesis and secretion of placental materials.

Original language	English (US)
Pages (from-to)	188-193
Number of pages	6
Journal	Neonatology
Volume	35
Issue number	3-4
DOIs	https://doi.org/10.1159/000241171
State	Published - 1979

Keywords

Hormones
Human placenta
Perfusion
Proteins
Secretion

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Developmental Biology

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10.1159/000241171

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AU - Dancis, J.

AU - Ghosh, N. K.

AU - Jansen, V.

AU - Schneider, H.

AU - Fallon, R. J.

AU - Cox, R. P.

PY - 1979

Y1 - 1979

N2 - A relatively simple perfusion technique of human placenta has been applied to the study of secretory proteins. Preferential secretion into the maternal circulation of human chorionic gonadotropin (HCG), human chorionic somatomammotropin (HCS), follicle-stimulating hormone (FSH), and placental alkaline phosphatase has been demonstrated, contrasting with the bidirectional secretion of progesterone. Evidence is presented for the net synthesis of HCS during perfusion. The technique offers advantages in the study of synthesis and secretion of placental materials.

AB - A relatively simple perfusion technique of human placenta has been applied to the study of secretory proteins. Preferential secretion into the maternal circulation of human chorionic gonadotropin (HCG), human chorionic somatomammotropin (HCS), follicle-stimulating hormone (FSH), and placental alkaline phosphatase has been demonstrated, contrasting with the bidirectional secretion of progesterone. Evidence is presented for the net synthesis of HCS during perfusion. The technique offers advantages in the study of synthesis and secretion of placental materials.

KW - Hormones

KW - Human placenta

KW - Perfusion

KW - Proteins

KW - Secretion

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Secretory proteins in the perfused human placenta

Abstract

Keywords

ASJC Scopus subject areas

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