Selected Disorders of Malabsorption

Zafreen Siddiqui, Amimi S. Osayande

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Malabsorption syndrome encompasses numerous clinical entities that result in chronic diarrhea, abdominal distention, and failure to thrive. These disorders may be congenital or acquired and include cystic fibrosis and Shwachman-Diamond syndrome; the rare congenital lactase deficiency; glucose-galactose malabsorption; sucrase-isomaltase deficiency; adult-type hypolactasia leading to acquired lactose intolerance. The pathology may be due to impairment in absorption or digestion of nutrients resulting in Nutritional deficiency, gastrointestinal symptoms, and extra gastrointestinal symptoms. Treatment is aimed at correcting the deficiencies and symptoms to improve quality of life. Common disorders of malabsorption celiac disease, pernicious anemia, and lactase deficiency are discussed in this article.

Original languageEnglish (US)
Pages (from-to)395-414
Number of pages20
JournalPrimary Care - Clinics in Office Practice
Issue number3
StatePublished - Sep 1 2011


  • Celiac
  • Lactase deficiency
  • Lactose intolerance
  • Pernicious anemia
  • Sprue
  • Vitamin B

ASJC Scopus subject areas

  • Pharmacology (medical)


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