In recent years, a considerable effort has been made to promote the use of liposomes as potential carriers for systemically administered chemotherapeutic agents. It is our belief that much of this proselytizing has ignored the normal and unavoidable fate of systemically administered liposomes, which is clearance by the reticuloendothelial system. Rather than attempting to avoid this phenomenon, we suggest that this occurence could be advantageous for the selective delivery of agents to cells of the monocyte-macrophage series involved in various disease states.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of Biological Response Modifiers|
|State||Published - Dec 1 1983|
ASJC Scopus subject areas
- Cancer Research