Selective sensing of zinc ions with a PARACEST contrast agent

Robert Trokowski; Jimin Ren; Ferenc Krisztián Kálmán; A. Dean Sherry

doi:10.1002/anie.200502173

Selective sensing of zinc ions with a PARACEST contrast agent

Robert Trokowski, Jimin Ren, Ferenc Krisztián Kálmán, A. Dean Sherry

Research output: Contribution to journal › Article › peer-review

128 Scopus citations

Abstract

A europium complex capable of selectively binding zinc (see picture) has been developed as a new paramagnetic chemical exchange saturation transfer (PARACEST) imaging agent for use in magnetic resonance imaging (MRI). A hydroxide group on the bound Zn ion increases the rate of water exchange on the Eu ion. (Chemical Equation Presented)

Original language	English (US)
Pages (from-to)	6920-6923
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	44
Issue number	42
DOIs	https://doi.org/10.1002/anie.200502173
State	Published - Oct 28 2005

Keywords

Imaging agents
Lanthanides
Proton exchange
Saturation transfer
Zinc

ASJC Scopus subject areas

Catalysis
General Chemistry

Access to Document

10.1002/anie.200502173

Cite this

@article{324551cedd1b4211909c754e7ee500e8,

title = "Selective sensing of zinc ions with a PARACEST contrast agent",

abstract = "A europium complex capable of selectively binding zinc (see picture) has been developed as a new paramagnetic chemical exchange saturation transfer (PARACEST) imaging agent for use in magnetic resonance imaging (MRI). A hydroxide group on the bound Zn ion increases the rate of water exchange on the Eu ion. (Chemical Equation Presented)",

keywords = "Imaging agents, Lanthanides, Proton exchange, Saturation transfer, Zinc",

author = "Robert Trokowski and Jimin Ren and K{\'a}lm{\'a}n, {Ferenc Kriszti{\'a}n} and Sherry, {A. Dean}",

year = "2005",

month = oct,

day = "28",

doi = "10.1002/anie.200502173",

language = "English (US)",

volume = "44",

pages = "6920--6923",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "42",

}

TY - JOUR

T1 - Selective sensing of zinc ions with a PARACEST contrast agent

AU - Trokowski, Robert

AU - Ren, Jimin

AU - Kálmán, Ferenc Krisztián

AU - Sherry, A. Dean

PY - 2005/10/28

Y1 - 2005/10/28

N2 - A europium complex capable of selectively binding zinc (see picture) has been developed as a new paramagnetic chemical exchange saturation transfer (PARACEST) imaging agent for use in magnetic resonance imaging (MRI). A hydroxide group on the bound Zn ion increases the rate of water exchange on the Eu ion. (Chemical Equation Presented)

AB - A europium complex capable of selectively binding zinc (see picture) has been developed as a new paramagnetic chemical exchange saturation transfer (PARACEST) imaging agent for use in magnetic resonance imaging (MRI). A hydroxide group on the bound Zn ion increases the rate of water exchange on the Eu ion. (Chemical Equation Presented)

KW - Imaging agents

KW - Lanthanides

KW - Proton exchange

KW - Saturation transfer

KW - Zinc

UR - http://www.scopus.com/inward/record.url?scp=27544442676&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=27544442676&partnerID=8YFLogxK

U2 - 10.1002/anie.200502173

DO - 10.1002/anie.200502173

M3 - Article

C2 - 16206314

AN - SCOPUS:27544442676

SN - 1433-7851

VL - 44

SP - 6920

EP - 6923

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 42

ER -

Selective sensing of zinc ions with a PARACEST contrast agent

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this