Self-expanding metallic stents: Preliminary evaluation in an atherosclerotic model

N. Rollins, K. C. Wright, C. Charnsangavej, S. Wallace, C. Gianturco

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

The performance of the self-expanding stainless steel (Gianturco) stent in atherosclerotic arteries was examined in a rabbit model. Atherosclerosis was induced by supplementing rabbit chow with 6% peanut oil and 2% cholesterol followed by endothelial disruption of the abdominal aorta with a balloon catheter and continuation on the atherogenic diet for the remainder of the study. Eighteen stents, 1 cm in length and 4 or 5 mm in diameter when fully expanded, were placed in atherosclerotic stenotic lesions in six rabbits. Luminal distention was consistently achieved. At 8 weeks follow-up, no luminal narrowing, stent migration, thrombus formation or branch vessel occlusion had occurred. Atherosclerotic neointimal proliferation occurred around the stent wires following placement, but did not cause significant luminal narrowing.

Original languageEnglish (US)
Pages (from-to)739-742
Number of pages4
JournalRadiology
Volume163
Issue number3
DOIs
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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