TY - JOUR
T1 - Self-expanding metallic stents
T2 - Preliminary evaluation in an atherosclerotic model
AU - Rollins, N.
AU - Wright, K. C.
AU - Charnsangavej, C.
AU - Wallace, S.
AU - Gianturco, C.
PY - 1987/1/1
Y1 - 1987/1/1
N2 - The performance of the self-expanding stainless steel (Gianturco) stent in atherosclerotic arteries was examined in a rabbit model. Atherosclerosis was induced by supplementing rabbit chow with 6% peanut oil and 2% cholesterol followed by endothelial disruption of the abdominal aorta with a balloon catheter and continuation on the atherogenic diet for the remainder of the study. Eighteen stents, 1 cm in length and 4 or 5 mm in diameter when fully expanded, were placed in atherosclerotic stenotic lesions in six rabbits. Luminal distention was consistently achieved. At 8 weeks follow-up, no luminal narrowing, stent migration, thrombus formation or branch vessel occlusion had occurred. Atherosclerotic neointimal proliferation occurred around the stent wires following placement, but did not cause significant luminal narrowing.
AB - The performance of the self-expanding stainless steel (Gianturco) stent in atherosclerotic arteries was examined in a rabbit model. Atherosclerosis was induced by supplementing rabbit chow with 6% peanut oil and 2% cholesterol followed by endothelial disruption of the abdominal aorta with a balloon catheter and continuation on the atherogenic diet for the remainder of the study. Eighteen stents, 1 cm in length and 4 or 5 mm in diameter when fully expanded, were placed in atherosclerotic stenotic lesions in six rabbits. Luminal distention was consistently achieved. At 8 weeks follow-up, no luminal narrowing, stent migration, thrombus formation or branch vessel occlusion had occurred. Atherosclerotic neointimal proliferation occurred around the stent wires following placement, but did not cause significant luminal narrowing.
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U2 - 10.1148/radiology.163.3.3575726
DO - 10.1148/radiology.163.3.3575726
M3 - Article
C2 - 3575726
AN - SCOPUS:0023216207
SN - 0033-8419
VL - 163
SP - 739
EP - 742
JO - Radiology
JF - Radiology
IS - 3
ER -