TY - JOUR
T1 - Sensing a pattern
T2 - Overlapping immunity in bacteria and eukaryotes
AU - Forsberg, Kevin
N1 - Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2022/10/12
Y1 - 2022/10/12
N2 - Pathogen-associated molecular patterns are recognized by dedicated receptors in eukaryotes to trigger an immune response. A recent study by Gao, Wilkinson, Strecker, et al. now extends this paradigm to bacteria, demonstrating that they use similar receptors to detect conserved phage proteins and activate analogous immunity against these viral invaders.
AB - Pathogen-associated molecular patterns are recognized by dedicated receptors in eukaryotes to trigger an immune response. A recent study by Gao, Wilkinson, Strecker, et al. now extends this paradigm to bacteria, demonstrating that they use similar receptors to detect conserved phage proteins and activate analogous immunity against these viral invaders.
UR - http://www.scopus.com/inward/record.url?scp=85139449756&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85139449756&partnerID=8YFLogxK
U2 - 10.1016/j.chom.2022.09.006
DO - 10.1016/j.chom.2022.09.006
M3 - Comment/debate
C2 - 36228582
AN - SCOPUS:85139449756
SN - 1931-3128
VL - 30
SP - 1346
EP - 1349
JO - Cell Host and Microbe
JF - Cell Host and Microbe
IS - 10
ER -