Sensitivity of in vivo mrs of the n‐δ proton in proximal histidine of deoxymyoglobin

Z. Wang; D. J. Wang; E. A. Noyszewski; A. R. Bogdan; J. C. Haselgrove; R. Reddy; R. A. Zimmerman; J. S. Leigh

doi:10.1002/mrm.1910270217

Sensitivity of in vivo mrs of the n‐δ proton in proximal histidine of deoxymyoglobin

Z. Wang, D. J. Wang, E. A. Noyszewski, A. R. Bogdan, J. C. Haselgrove, R. Reddy, R. A. Zimmerman, J. S. Leigh

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Abstract

The sensitivity of in vivo MRS of the N‐δ proton of the proximal histidine of deoxymyoglobin in human skeletal muscles is discussed. Longitudinal relaxation time T₁ of this deoxymyoglobin signal was measured in cuffed human forearms at 1.5 T and found to be 9.9 ms. Deoxymyoglobin spectra can be obtained from a forearm in seconds. The detection sensitivity of deoxymyoglobin in fully ischemic skeletal muscles and that of³¹P MRS of PCr in normal resting muscles are compared.

Original language	English (US)
Pages (from-to)	362-367
Number of pages	6
Journal	Magnetic resonance in medicine
Volume	27
Issue number	2
DOIs	https://doi.org/10.1002/mrm.1910270217
State	Published - Oct 1992

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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title = "Sensitivity of in vivo mrs of the n‐δ proton in proximal histidine of deoxymyoglobin",

abstract = "The sensitivity of in vivo MRS of the N‐δ proton of the proximal histidine of deoxymyoglobin in human skeletal muscles is discussed. Longitudinal relaxation time T1 of this deoxymyoglobin signal was measured in cuffed human forearms at 1.5 T and found to be 9.9 ms. Deoxymyoglobin spectra can be obtained from a forearm in seconds. The detection sensitivity of deoxymyoglobin in fully ischemic skeletal muscles and that of31P MRS of PCr in normal resting muscles are compared.",

author = "Z. Wang and Wang, {D. J.} and Noyszewski, {E. A.} and Bogdan, {A. R.} and Haselgrove, {J. C.} and R. Reddy and Zimmerman, {R. A.} and Leigh, {J. S.}",

year = "1992",

month = oct,

doi = "10.1002/mrm.1910270217",

language = "English (US)",

volume = "27",

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journal = "Magnetic resonance in medicine",

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T1 - Sensitivity of in vivo mrs of the n‐δ proton in proximal histidine of deoxymyoglobin

AU - Wang, Z.

AU - Wang, D. J.

AU - Noyszewski, E. A.

AU - Bogdan, A. R.

AU - Haselgrove, J. C.

AU - Reddy, R.

AU - Zimmerman, R. A.

AU - Leigh, J. S.

PY - 1992/10

Y1 - 1992/10

N2 - The sensitivity of in vivo MRS of the N‐δ proton of the proximal histidine of deoxymyoglobin in human skeletal muscles is discussed. Longitudinal relaxation time T1 of this deoxymyoglobin signal was measured in cuffed human forearms at 1.5 T and found to be 9.9 ms. Deoxymyoglobin spectra can be obtained from a forearm in seconds. The detection sensitivity of deoxymyoglobin in fully ischemic skeletal muscles and that of31P MRS of PCr in normal resting muscles are compared.

AB - The sensitivity of in vivo MRS of the N‐δ proton of the proximal histidine of deoxymyoglobin in human skeletal muscles is discussed. Longitudinal relaxation time T1 of this deoxymyoglobin signal was measured in cuffed human forearms at 1.5 T and found to be 9.9 ms. Deoxymyoglobin spectra can be obtained from a forearm in seconds. The detection sensitivity of deoxymyoglobin in fully ischemic skeletal muscles and that of31P MRS of PCr in normal resting muscles are compared.

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JO - Magnetic resonance in medicine

JF - Magnetic resonance in medicine

IS - 2

ER -

Sensitivity of in vivo mrs of the n‐δ proton in proximal histidine of deoxymyoglobin

Abstract

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