Sepsis-induced cardiac mitochondrial dysfunction involves altered mitochondrial-localization of tyrosine kinase Src and tyrosine phosphatase SHP2

Medicine & Life Sciences

• Non-Receptor Type 11 Protein Tyrosine Phosphatase 100%
• src-Family Kinases 72%
• Sepsis 49%
• Heart 32%
• Aconitate Hydratase 29%
• Mitochondria 25%
• Mitochondrial Proteins 23%
• Tyrosine 18%
• Cyclophilin D 16%
• Oxidative Stress 14%
• Phosphorylation 13%
• In Vitro Techniques 13%
• Porins 13%
• Subcellular Fractions 13%
• Cytochromes 11%
• Streptococcus pneumoniae 10%
• Immunoprecipitation 9%
• Pneumonia 8%
• Western Blotting 6%
• Injections 5%
• Proteins 3%
• Therapeutics 3%

Agriculture & Biology

• tyrosine 55%
• phosphotransferases (kinases) 51%
• heart 47%
• aconitate hydratase 33%
• mitochondria 27%
• rats 25%
• phosphorylation 21%
• oxidative stress 19%
• cyclophilins 17%
• porins 15%
• Streptococcus pneumoniae 15%
• subcellular fractions 13%
• structural proteins 13%
• pneumonia 13%
• cytochromes 11%
• Western blotting 10%
• pretreatment 9%
• injection 8%
• proteins 8%
• tissues 5%

Chemical Compounds

• Tyrosine 55%
• Signalling Molecule 38%
• Oxidative Stress 30%
• Intratracheal 24%
• Cytochrome C 21%
• Protein 18%
• Percent Reduction 17%
• Marker 13%