Sequence of mRNA coding for bindin, a species-specific sea urchin sperm protein required for fertilization

B. Gao, L. E. Klein, R. J. Britten, E. H. Davidson

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Bindin, a major protein of the sea urchin acrosome granule, mediates the species-specific adhesion and binding of sperm to egg required to effect fertilization. We report the isolation and sequence of bindin cDNA clones prepared from Strongylocentrotus purpuratus testis RNA. The bindin gene appears to be productively expressed only in males and only in testes. The protein is produced from a 51-kDa precursor, which is subsequently processed to yield the mature 24-kDa bindin protein.

Original languageEnglish (US)
Pages (from-to)8634-8638
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume83
Issue number22
StatePublished - 1986

Fingerprint

Sea Urchins
Fertilization
Spermatozoa
Messenger RNA
Testis
Strongylocentrotus purpuratus
Acrosome
Proteins
Ovum
Complementary DNA
Clone Cells
RNA
Genes

ASJC Scopus subject areas

  • General
  • Genetics

Cite this

Sequence of mRNA coding for bindin, a species-specific sea urchin sperm protein required for fertilization. / Gao, B.; Klein, L. E.; Britten, R. J.; Davidson, E. H.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, No. 22, 1986, p. 8634-8638.

Research output: Contribution to journalArticle

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