Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: Requirement for mTORC1 activity associates with ER-alpha expression

Medicine & Life Sciences

• serum-glucocorticoid regulated kinase 100%
• Mechanistic Target of Rapamycin Complex 1 73%
• Sirolimus 44%
• Breast Neoplasms 37%
• TOR Serine-Threonine Kinases 29%
• Phosphorylation 18%
• Cell Line 12%
• MCF-7 Cells 11%
• Small Interfering RNA 8%
• Growth 8%
• Mechanistic Target of Rapamycin Complex 2 7%
• 70-kDa Ribosomal Protein S6 Kinases 7%
• Everolimus 6%
• Estrogen Receptor alpha 6%
• Phosphotransferases 4%
• Breast 4%
• Insulin 3%
• Cell Proliferation 3%
• Neoplasms 3%