Serum Cystatin C as a Novel Marker to Differentiate Pseudoazotemia in the Setting of Intraperitoneal Urine Extravasation

Solomon L. Woldu, Justin T. Matulay, Mark V. Silva, Jennifer J. Ahn, Ronald Zviti, Sarah M. Lambert, Shumyle Alam, Pasquale Casale

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Urinary ascites results in pseudoazotemia due to urinary creatinine reabsorption across the peritoneum. We report a case of a pyeloplasty complicated by urine extravasation, in which the diagnosis was aided by discrepant findings of an elevated serum creatinine level but a stable cystatin C level. Cystatin C is a marker of renal function but is not typically excreted into the urine and therefore can be used to differentiate pseudoazotemia from true azotemia and is a better marker of renal function in the setting of known urinary ascites. These findings are relevant for patients with potential traumatic or nontraumatic sources of urine extravasation.

Original languageEnglish (US)
Pages (from-to)918-920
Number of pages3
JournalUrology
Volume85
Issue number4
DOIs
StatePublished - Apr 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • Urology

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