Serum neuron-specific enolase in metastatic Merkel cell tumors

L. Giannone, D. H. Johnson, W. W. Grosh, B. W. Davis, P. J. Marangos, F. A. Greco

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Abstract

Three patients with widely disseminated Merkel cell tumors of the skin are presented. In all three cases, neuron-specific enolase (NSE) was demonstrated in neoplastic tissue by immunohistochemical staining, and serum NSE levels were also elevated in all three patients. Serum NSE may prove to be a useful tumor marker in this and other malignancies of neuroendocrine origin.

Original languageEnglish (US)
Pages (from-to)357-362
Number of pages6
JournalMedical and Pediatric Oncology
Volume13
Issue number6
DOIs
StatePublished - 1985

Fingerprint

Merkel Cell Carcinoma
Phosphopyruvate Hydratase
Serum
Tumor Biomarkers
Staining and Labeling
Skin
Neoplasms

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Cancer Research

Cite this

Giannone, L., Johnson, D. H., Grosh, W. W., Davis, B. W., Marangos, P. J., & Greco, F. A. (1985). Serum neuron-specific enolase in metastatic Merkel cell tumors. Medical and Pediatric Oncology, 13(6), 357-362. https://doi.org/10.1002/mpo.2950130611

Serum neuron-specific enolase in metastatic Merkel cell tumors. / Giannone, L.; Johnson, D. H.; Grosh, W. W.; Davis, B. W.; Marangos, P. J.; Greco, F. A.

In: Medical and Pediatric Oncology, Vol. 13, No. 6, 1985, p. 357-362.

Research output: Contribution to journalArticle

Giannone, L, Johnson, DH, Grosh, WW, Davis, BW, Marangos, PJ & Greco, FA 1985, 'Serum neuron-specific enolase in metastatic Merkel cell tumors', Medical and Pediatric Oncology, vol. 13, no. 6, pp. 357-362. https://doi.org/10.1002/mpo.2950130611
Giannone, L. ; Johnson, D. H. ; Grosh, W. W. ; Davis, B. W. ; Marangos, P. J. ; Greco, F. A. / Serum neuron-specific enolase in metastatic Merkel cell tumors. In: Medical and Pediatric Oncology. 1985 ; Vol. 13, No. 6. pp. 357-362.
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