Serum neuron‐specific enolase in metastatic merkel cell tumors

L. Giannone; D. H. Johnson; W. W. Grosh; B. W. Davis; P. J. Marangos; F. A. Greco

doi:10.1002/mpo.2950130611

Serum neuron‐specific enolase in metastatic merkel cell tumors

L. Giannone, D. H. Johnson, W. W. Grosh, B. W. Davis, P. J. Marangos, F. A. Greco

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Abstract

Three patients with widely disseminated Merkel cell tumors of the skin are presented. In all three cases, neuron‐specific enolase (NSE) was demonstrated in neoplastic tissue by immunohistochemical staining, and serum NSE levels were also elevated in all three patients. Serum NSE may prove to be a useful tumor marker in this and other malignancies of neuroendocrine origin.

Original language	English (US)
Pages (from-to)	357-362
Number of pages	6
Journal	Medical and Pediatric Oncology
Volume	13
Issue number	6
DOIs	https://doi.org/10.1002/mpo.2950130611
State	Published - 1985

Keywords

Merkel cell tumor
neuron‐specific enolase

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Oncology
Cancer Research

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abstract = "Three patients with widely disseminated Merkel cell tumors of the skin are presented. In all three cases, neuron‐specific enolase (NSE) was demonstrated in neoplastic tissue by immunohistochemical staining, and serum NSE levels were also elevated in all three patients. Serum NSE may prove to be a useful tumor marker in this and other malignancies of neuroendocrine origin.",

keywords = "Merkel cell tumor, neuron‐specific enolase",

author = "L. Giannone and Johnson, {D. H.} and Grosh, {W. W.} and Davis, {B. W.} and Marangos, {P. J.} and Greco, {F. A.}",

year = "1985",

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AU - Giannone, L.

AU - Johnson, D. H.

AU - Grosh, W. W.

AU - Davis, B. W.

AU - Marangos, P. J.

AU - Greco, F. A.

PY - 1985

Y1 - 1985

N2 - Three patients with widely disseminated Merkel cell tumors of the skin are presented. In all three cases, neuron‐specific enolase (NSE) was demonstrated in neoplastic tissue by immunohistochemical staining, and serum NSE levels were also elevated in all three patients. Serum NSE may prove to be a useful tumor marker in this and other malignancies of neuroendocrine origin.

AB - Three patients with widely disseminated Merkel cell tumors of the skin are presented. In all three cases, neuron‐specific enolase (NSE) was demonstrated in neoplastic tissue by immunohistochemical staining, and serum NSE levels were also elevated in all three patients. Serum NSE may prove to be a useful tumor marker in this and other malignancies of neuroendocrine origin.

KW - Merkel cell tumor

KW - neuron‐specific enolase

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Serum neuron‐specific enolase in metastatic merkel cell tumors

Abstract

Keywords

ASJC Scopus subject areas

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