Sex-specific ventricular and vascular adaptations to exercise

Jill N. Barnes, Qi Fu

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations


Increasing data suggest that there are sex differences in ventricular and vascular adaptations to aerobic (endurance) exercise, which may be attributed to different physical and physiological features in men and women. Despite that cardiovascular control during acute exercise at the same relative work rate (e.g., the percentage of peak oxygen uptake) appears to be similar between the sexes, women have blunted responses or adaptations to prolonged (e.g., ≥1 year) exercise training compared with men. Currently, there is little evidence to suggest that exercise-induced vascular adaptations are different between men and women. Furthermore, sex differences in skeletal muscle adaptations to exercise, and how this influences cardiovascular function, remain unclear. Identifying potential differences and the mechanisms behind such exercise-induced adaptations is important for the optimization of exercise interventions between men and women across the life span.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Number of pages18
StatePublished - 2018

Publication series

NameAdvances in Experimental Medicine and Biology
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019


  • Aerobic fitness
  • Cardiac output
  • Cardiovascular adaptation
  • Endurance training
  • Exercise
  • Heart rate
  • Oxygen uptake
  • Stroke volume

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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