TY - JOUR
T1 - Sexual dysfunction in patients with multiple sclerosis
T2 - A multidisciplinary approach to evaluation and management
AU - Fletcher, Sophie G.
AU - Castro-Borrero, Wanda
AU - Remington, Gina
AU - Treadaway, Katherine
AU - Lemack, Gary E
AU - Frohman, Elliot
N1 - Funding Information:
This project was supported by the Once Upon A Time Foundation, the Cain/Denius Comprehensive Center for Mobility Research, the Irene Wadel and Robert Atha Fund, the Kenney Marie Dixon Pickens fund, and the Jean Ann and Steve Brock Fund for Medical Sciences (all to EM Frohman). SG Fletcher would like to acknowledge The Felecia Cain Fellowship Endowment for Female Pelvic Medicine, Reconstructive Surgery and Neurourology.
PY - 2009
Y1 - 2009
N2 - Multiple sclerosis (MS) is the most common cause of progressive neurological disability in young adults. In addition to spasticity, tremors, weakness, sensory disturbances, depression, cognitive problems, and bladder or bowel dysfunction, sexual dysfunction (SD) is also a prevalent and destructive manifestation of the disease that severely affects quality of life. Evaluation of this disorder requires insight into the primary (changes that directly affect libido, sexual response and orgasm due to direct damage to the nervous system), secondary (complaints which are related to the physical disability of MS, such as fatigue, muscle rigidity, weakness and spasms), and tertiary (emotional, social and cultural aspects of MS) components of MS-associated SD. Given the complexity and multifactorial nature of SD, a multidisciplinary approach is necessary when treating patients with MS. The aim of this Review is to provide a holistic approach to the evaluation and management of SD in patients with MS, incorporating the latest data from the fields of urology, neurology, nursing, social work, and psychology. What is currently known regarding the evaluation and management of SD in patients with MS will be presented from the perspective of these specialties.
AB - Multiple sclerosis (MS) is the most common cause of progressive neurological disability in young adults. In addition to spasticity, tremors, weakness, sensory disturbances, depression, cognitive problems, and bladder or bowel dysfunction, sexual dysfunction (SD) is also a prevalent and destructive manifestation of the disease that severely affects quality of life. Evaluation of this disorder requires insight into the primary (changes that directly affect libido, sexual response and orgasm due to direct damage to the nervous system), secondary (complaints which are related to the physical disability of MS, such as fatigue, muscle rigidity, weakness and spasms), and tertiary (emotional, social and cultural aspects of MS) components of MS-associated SD. Given the complexity and multifactorial nature of SD, a multidisciplinary approach is necessary when treating patients with MS. The aim of this Review is to provide a holistic approach to the evaluation and management of SD in patients with MS, incorporating the latest data from the fields of urology, neurology, nursing, social work, and psychology. What is currently known regarding the evaluation and management of SD in patients with MS will be presented from the perspective of these specialties.
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U2 - 10.1038/ncpuro1298
DO - 10.1038/ncpuro1298
M3 - Review article
C2 - 19198623
AN - SCOPUS:60149091160
SN - 1743-4270
VL - 6
SP - 96
EP - 107
JO - Nature Clinical Practice Urology
JF - Nature Clinical Practice Urology
IS - 2
ER -