Shaping the p53 Response with Nucleoporins

Melanie L. Yarbrough, Michael A. White, Beatriz M A Fontoura

Research output: Contribution to journalShort survey

4 Scopus citations

Abstract

In this issue, Singer et al. (2012) reveal that the nucleoporin Nup98 supports adaptation to genotoxic stress by protecting specific p53-induced mRNAs from exosome-dependent degradation, suggesting that wild-type Nup98 may possess tumor suppressor function.

Original languageEnglish (US)
Pages (from-to)665-666
Number of pages2
JournalMolecular cell
Volume48
Issue number5
DOIs
StatePublished - Dec 14 2012

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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