Shigella Puts the Brakes on the Host Cell Cycle

Research output: Contribution to journalArticle

Abstract

Intestinal epithelial cells serve as the major defense barrier against enteric bacterial infection. However, pathogens have devised remarkable schemes to usurp this formidable immune barrier. In a study recently published in Cell, Iwai et al. expand our understanding of how Shigella colonizes the epithelium by describing bacterial IpaB as a specific inhibitor of the eukaryotic cell division cycle.

Original languageEnglish (US)
Pages (from-to)141-142
Number of pages2
JournalCell Host and Microbe
Volume2
Issue number3
DOIs
StatePublished - Sep 13 2007

Fingerprint

Shigella
Eukaryotic Cells
Bacterial Infections
Cell Cycle
Epithelium
Epithelial Cells

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Cancer Research
  • Molecular Biology

Cite this

Shigella Puts the Brakes on the Host Cell Cycle. / Alto, Neal Mathew.

In: Cell Host and Microbe, Vol. 2, No. 3, 13.09.2007, p. 141-142.

Research output: Contribution to journalArticle

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