Shigella Puts the Brakes on the Host Cell Cycle

Research output: Contribution to journalShort survey

Abstract

Intestinal epithelial cells serve as the major defense barrier against enteric bacterial infection. However, pathogens have devised remarkable schemes to usurp this formidable immune barrier. In a study recently published in Cell, Iwai et al. expand our understanding of how Shigella colonizes the epithelium by describing bacterial IpaB as a specific inhibitor of the eukaryotic cell division cycle.

Original languageEnglish (US)
Pages (from-to)141-142
Number of pages2
JournalCell Host and Microbe
Volume2
Issue number3
DOIs
StatePublished - Sep 13 2007

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ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Virology

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