Shigella Puts the Brakes on the Host Cell Cycle

Research output: Contribution to journalShort survey


Intestinal epithelial cells serve as the major defense barrier against enteric bacterial infection. However, pathogens have devised remarkable schemes to usurp this formidable immune barrier. In a study recently published in Cell, Iwai et al. expand our understanding of how Shigella colonizes the epithelium by describing bacterial IpaB as a specific inhibitor of the eukaryotic cell division cycle.

Original languageEnglish (US)
Pages (from-to)141-142
Number of pages2
JournalCell Host and Microbe
Issue number3
StatePublished - Sep 13 2007


ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Virology

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