Should prostate cancer status be determined in patients undergoing radical cystoprostatectomy?

Oner Sanli, Omer Acar, Murad Celtik, Tayfun Oktar, Isin Kilicaraslan, Faruk Ozcan, Murat Tunc, Tarik Esen

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Introduction: We estimate the frequency of prostate cancers detected incidentally in radical cystoprostatectomy specimens and discuss whether the prostate cancer status should be determined in patients undergoing radical cystoprostatectomy. Materials and Methods: A total of 97 radical cystoprostatectomies without evidence of prostate cancer on digital rectal examination were performed for transitional cell carcinomas of the bladder between January 2001 and May 2004. The mean patient age at the time of surgery was 66.9 ± 9.52 (range 49-75) years. Results: The overall incidence of prostate cancer detected in radical cystoprostatectomy specimens was 21.6% (21/97 specimens). The mean tumor volume was found to be 0.93 ± 0.81 ml. The tumor volume was >0.5 ml in 12 cases (57.1%). The surgical margin was negative in all cases, and the disease was organ confined in 20 patients (95.2%). Capsular invasion was evident in 2 patients (9.5%), 1 of whom had lymph-node-positive disease. Conclusions: Despite the high prevalence of incidental prostate carcinomas among patients with bladder cancer undergoing cystoprostatectomy, the vast majority of the cancers are organ confined. However, the prostate cancer status should be determined on the basis of digital rectal examination and prostate-specific antigen in patients undergoing radical cystoprostatectomy - especially if prostate-sparing cystectomy is planned.

Original languageEnglish (US)
Pages (from-to)307-310
Number of pages4
JournalUrologia Internationalis
Volume77
Issue number4
DOIs
StatePublished - Nov 1 2006

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Prostatic Neoplasms
Digital Rectal Examination
Tumor Burden
Prostate
Transitional Cell Carcinoma
Cystectomy
Prostate-Specific Antigen
Urinary Bladder Neoplasms
Urinary Bladder
Lymph Nodes
Carcinoma
Incidence
Neoplasms

Keywords

  • Prostate cancer
  • Prostate cancer status determination
  • Radical cystoprostatectomy

ASJC Scopus subject areas

  • Urology

Cite this

Should prostate cancer status be determined in patients undergoing radical cystoprostatectomy? / Sanli, Oner; Acar, Omer; Celtik, Murad; Oktar, Tayfun; Kilicaraslan, Isin; Ozcan, Faruk; Tunc, Murat; Esen, Tarik.

In: Urologia Internationalis, Vol. 77, No. 4, 01.11.2006, p. 307-310.

Research output: Contribution to journalArticle

Sanli, O, Acar, O, Celtik, M, Oktar, T, Kilicaraslan, I, Ozcan, F, Tunc, M & Esen, T 2006, 'Should prostate cancer status be determined in patients undergoing radical cystoprostatectomy?', Urologia Internationalis, vol. 77, no. 4, pp. 307-310. https://doi.org/10.1159/000096333
Sanli, Oner ; Acar, Omer ; Celtik, Murad ; Oktar, Tayfun ; Kilicaraslan, Isin ; Ozcan, Faruk ; Tunc, Murat ; Esen, Tarik. / Should prostate cancer status be determined in patients undergoing radical cystoprostatectomy?. In: Urologia Internationalis. 2006 ; Vol. 77, No. 4. pp. 307-310.
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abstract = "Introduction: We estimate the frequency of prostate cancers detected incidentally in radical cystoprostatectomy specimens and discuss whether the prostate cancer status should be determined in patients undergoing radical cystoprostatectomy. Materials and Methods: A total of 97 radical cystoprostatectomies without evidence of prostate cancer on digital rectal examination were performed for transitional cell carcinomas of the bladder between January 2001 and May 2004. The mean patient age at the time of surgery was 66.9 ± 9.52 (range 49-75) years. Results: The overall incidence of prostate cancer detected in radical cystoprostatectomy specimens was 21.6{\%} (21/97 specimens). The mean tumor volume was found to be 0.93 ± 0.81 ml. The tumor volume was >0.5 ml in 12 cases (57.1{\%}). The surgical margin was negative in all cases, and the disease was organ confined in 20 patients (95.2{\%}). Capsular invasion was evident in 2 patients (9.5{\%}), 1 of whom had lymph-node-positive disease. Conclusions: Despite the high prevalence of incidental prostate carcinomas among patients with bladder cancer undergoing cystoprostatectomy, the vast majority of the cancers are organ confined. However, the prostate cancer status should be determined on the basis of digital rectal examination and prostate-specific antigen in patients undergoing radical cystoprostatectomy - especially if prostate-sparing cystectomy is planned.",
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AU - Ozcan, Faruk

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AU - Esen, Tarik

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AB - Introduction: We estimate the frequency of prostate cancers detected incidentally in radical cystoprostatectomy specimens and discuss whether the prostate cancer status should be determined in patients undergoing radical cystoprostatectomy. Materials and Methods: A total of 97 radical cystoprostatectomies without evidence of prostate cancer on digital rectal examination were performed for transitional cell carcinomas of the bladder between January 2001 and May 2004. The mean patient age at the time of surgery was 66.9 ± 9.52 (range 49-75) years. Results: The overall incidence of prostate cancer detected in radical cystoprostatectomy specimens was 21.6% (21/97 specimens). The mean tumor volume was found to be 0.93 ± 0.81 ml. The tumor volume was >0.5 ml in 12 cases (57.1%). The surgical margin was negative in all cases, and the disease was organ confined in 20 patients (95.2%). Capsular invasion was evident in 2 patients (9.5%), 1 of whom had lymph-node-positive disease. Conclusions: Despite the high prevalence of incidental prostate carcinomas among patients with bladder cancer undergoing cystoprostatectomy, the vast majority of the cancers are organ confined. However, the prostate cancer status should be determined on the basis of digital rectal examination and prostate-specific antigen in patients undergoing radical cystoprostatectomy - especially if prostate-sparing cystectomy is planned.

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