Silanol: A traceless directing group for Pd-catalyzed o -alkenylation of phenols

Chunhui Huang; Buddhadeb Chattopadhyay; Vladimir Gevorgyan

doi:10.1021/ja204924j

Silanol: A traceless directing group for Pd-catalyzed o -alkenylation of phenols

Chunhui Huang, Buddhadeb Chattopadhyay, Vladimir Gevorgyan

Research output: Contribution to journal › Article › peer-review

244 Scopus citations

Abstract

A silanol-directed, Pd(II)-catalyzed C-H alkenylation of phenols is reported. This work features silanol, as a novel traceless directing group, and a directed o-C-H alkenylation of phenols. This new method allows for efficient synthesis of diverse alkenylated phenols, including an estrone derivative.

Original language	English (US)
Pages (from-to)	12406-12409
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	133
Issue number	32
DOIs	https://doi.org/10.1021/ja204924j
State	Published - Aug 17 2011
Externally published	Yes

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja204924j

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title = "Silanol: A traceless directing group for Pd-catalyzed o -alkenylation of phenols",

abstract = "A silanol-directed, Pd(II)-catalyzed C-H alkenylation of phenols is reported. This work features silanol, as a novel traceless directing group, and a directed o-C-H alkenylation of phenols. This new method allows for efficient synthesis of diverse alkenylated phenols, including an estrone derivative.",

author = "Chunhui Huang and Buddhadeb Chattopadhyay and Vladimir Gevorgyan",

year = "2011",

month = aug,

day = "17",

doi = "10.1021/ja204924j",

language = "English (US)",

volume = "133",

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journal = "Journal of the American Chemical Society",

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TY - JOUR

T1 - Silanol

T2 - A traceless directing group for Pd-catalyzed o -alkenylation of phenols

AU - Huang, Chunhui

AU - Chattopadhyay, Buddhadeb

AU - Gevorgyan, Vladimir

PY - 2011/8/17

Y1 - 2011/8/17

N2 - A silanol-directed, Pd(II)-catalyzed C-H alkenylation of phenols is reported. This work features silanol, as a novel traceless directing group, and a directed o-C-H alkenylation of phenols. This new method allows for efficient synthesis of diverse alkenylated phenols, including an estrone derivative.

AB - A silanol-directed, Pd(II)-catalyzed C-H alkenylation of phenols is reported. This work features silanol, as a novel traceless directing group, and a directed o-C-H alkenylation of phenols. This new method allows for efficient synthesis of diverse alkenylated phenols, including an estrone derivative.

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U2 - 10.1021/ja204924j

DO - 10.1021/ja204924j

M3 - Article

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JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 32

ER -

Silanol: A traceless directing group for Pd-catalyzed o -alkenylation of phenols

Abstract

ASJC Scopus subject areas

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