Silanol: A traceless directing group for Pd-catalyzed o -alkenylation of phenols

Chunhui Huang, Buddhadeb Chattopadhyay, Vladimir Gevorgyan

Research output: Contribution to journalArticle

188 Citations (Scopus)

Abstract

A silanol-directed, Pd(II)-catalyzed C-H alkenylation of phenols is reported. This work features silanol, as a novel traceless directing group, and a directed o-C-H alkenylation of phenols. This new method allows for efficient synthesis of diverse alkenylated phenols, including an estrone derivative.

Original languageEnglish (US)
Pages (from-to)12406-12409
Number of pages4
JournalJournal of the American Chemical Society
Volume133
Issue number32
DOIs
StatePublished - Aug 17 2011
Externally publishedYes

Fingerprint

Alkenylation
Phenols
Estrone
Derivatives
silanol

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Silanol : A traceless directing group for Pd-catalyzed o -alkenylation of phenols. / Huang, Chunhui; Chattopadhyay, Buddhadeb; Gevorgyan, Vladimir.

In: Journal of the American Chemical Society, Vol. 133, No. 32, 17.08.2011, p. 12406-12409.

Research output: Contribution to journalArticle

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