Silent functional magnetic resonance imaging demonstrates focal activation in rapid eye movement sleep

Karl Olof Lövblad, R. Thomas, P. M. Jakob, T. Scammell, C. Bassetti, M. Griswold, J. Ives, J. Matheson, R. R. Edelman, S. Warach

Research output: Contribution to journalArticle

77 Scopus citations

Abstract

Functional imaging of human sleep has been performed with nuclear medicine methods, but MRI has been difficult to implement, in part because of the noise associated with echo-planar imaging as well as the difficulty in reading physiologic signals in the MRI environment. We describe a silent MR sequence that can record brain activation over many hours with simultaneous acquisition of an EEG. This shows activation of occipital cortex and deactivation of frontal cortex during REM sleep, in agreement with previous studies using other techniques.

Original languageEnglish (US)
Pages (from-to)2193-2195
Number of pages3
JournalNeurology
Volume53
Issue number9
DOIs
StatePublished - Dec 10 1999

Keywords

  • Functional imaging
  • MRI
  • REM sleep
  • Sleep

ASJC Scopus subject areas

  • Clinical Neurology

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    Lövblad, K. O., Thomas, R., Jakob, P. M., Scammell, T., Bassetti, C., Griswold, M., Ives, J., Matheson, J., Edelman, R. R., & Warach, S. (1999). Silent functional magnetic resonance imaging demonstrates focal activation in rapid eye movement sleep. Neurology, 53(9), 2193-2195. https://doi.org/10.1212/wnl.53.9.2193