Silent supraglottic carcinoma

L. Garth Close, M. Merkel, J. Reisch, D. K. Burns, S. D. Schaefer

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In a review of 51 consecutive patients with previously untreated squamous cell carcinoma of the supraglottic larynx, five (9.8%) patients were found to have no mucosal abnormality on initial evaluation by both computed tomography (CT) and direct laryngoscopy. All five patients who manifested submucosal disease had at least one endoscopic procedure done with a biopsy negative for cancer before definitive diagnosis, resulting in an average delay from initial endoscopy to diagnosis of 19.8 weeks. These inapparent or 'silent' neoplasms present unique problems in regard to establishing a diagnosis by routine biopsy techniques, even though CT reliably demonstrates their presence. Early diagnosis requires aggressive biopsy techniques based on CT findings.

Original languageEnglish (US)
Pages (from-to)286-295
Number of pages10
JournalOtolaryngology - Head and Neck Surgery
Volume99
Issue number3
StatePublished - 1988

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Tomography
Carcinoma
Biopsy
Laryngoscopy
Larynx
Endoscopy
Early Diagnosis
Squamous Cell Carcinoma
Neoplasms

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Garth Close, L., Merkel, M., Reisch, J., Burns, D. K., & Schaefer, S. D. (1988). Silent supraglottic carcinoma. Otolaryngology - Head and Neck Surgery, 99(3), 286-295.

Silent supraglottic carcinoma. / Garth Close, L.; Merkel, M.; Reisch, J.; Burns, D. K.; Schaefer, S. D.

In: Otolaryngology - Head and Neck Surgery, Vol. 99, No. 3, 1988, p. 286-295.

Research output: Contribution to journalArticle

Garth Close, L, Merkel, M, Reisch, J, Burns, DK & Schaefer, SD 1988, 'Silent supraglottic carcinoma', Otolaryngology - Head and Neck Surgery, vol. 99, no. 3, pp. 286-295.
Garth Close L, Merkel M, Reisch J, Burns DK, Schaefer SD. Silent supraglottic carcinoma. Otolaryngology - Head and Neck Surgery. 1988;99(3):286-295.
Garth Close, L. ; Merkel, M. ; Reisch, J. ; Burns, D. K. ; Schaefer, S. D. / Silent supraglottic carcinoma. In: Otolaryngology - Head and Neck Surgery. 1988 ; Vol. 99, No. 3. pp. 286-295.
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