3,3-Disubstituted cyclopropenes have been readily prepared in a multigram scale via two different methods: (1) dehydrohalogenation of bromocyclopropanes, and (2) Rh-catalyzed addition of carbenoids to trimethylsilylacetylene followed by desilylation. Highly diastereoselective Pd-catalyzed hydrostannation and highly enantioselective Rh-catalyzed hydroboration of 3,3-disubstituted cyclopropenes afforded useful cyclopropylmetal building blocks in high yields.
|Original language||English (US)|
|Number of pages||5|
|State||Published - Apr 2 2004|
- Transition metal catalysis
ASJC Scopus subject areas
- Organic Chemistry