Simple synthesis of benzofuranoid neolignans from Myristica fragrans

László Juhász, László Kürti, Sándor Antus

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The total synthesis of four neolignans - fragnasols A (1), B (2), and C (3) and dehydrodiisoeugenol (4) - starting from the readily available phenol derivative isoeugenol (5) was accomplished. The key step of the synthesis of these natural products is a novel type of dimerization of 5 into 4 with iodobenzene diacetate.

Original languageEnglish (US)
Pages (from-to)866-870
Number of pages5
JournalJournal of Natural Products
Volume63
Issue number6
DOIs
StatePublished - Jun 2000

Fingerprint

isoeugenol
Myristica fragrans
Lignans
lignans
Dimerization
Phenol
Biological Products
synthesis
dimerization
phenol
chemical derivatives
Derivatives
dehydrodiisoeugenol
iodobenzene

ASJC Scopus subject areas

  • Plant Science
  • Chemistry (miscellaneous)
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Cite this

Simple synthesis of benzofuranoid neolignans from Myristica fragrans. / Juhász, László; Kürti, László; Antus, Sándor.

In: Journal of Natural Products, Vol. 63, No. 6, 06.2000, p. 866-870.

Research output: Contribution to journalArticle

Juhász, László ; Kürti, László ; Antus, Sándor. / Simple synthesis of benzofuranoid neolignans from Myristica fragrans. In: Journal of Natural Products. 2000 ; Vol. 63, No. 6. pp. 866-870.
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