Simple synthesis of benzofuranoid neolignans from Myristica fragrans

László Juhász, László Kürti, Sándor Antus

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

The total synthesis of four neolignans - fragnasols A (1), B (2), and C (3) and dehydrodiisoeugenol (4) - starting from the readily available phenol derivative isoeugenol (5) was accomplished. The key step of the synthesis of these natural products is a novel type of dimerization of 5 into 4 with iodobenzene diacetate.

Original languageEnglish (US)
Pages (from-to)866-870
Number of pages5
JournalJournal of Natural Products
Volume63
Issue number6
DOIs
StatePublished - Jun 1 2000

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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