Simplifying the preevacuation testing strategy for patients with molar pregnancy

Lynne M. Knowles, Richard D. Drake, Raheela Ashfaq, Diego H. Castrillon, David S. Miller, John O. Schorge

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: To review our institution's preevacuation testing strategy for suspected molar pregnancy to determine whether a simplified approach might be indicated. STUDY DESIGN: Patients diagnosed with molar pregnancy from 1999 to 2004 were identified. Clinical data were retrospectively extracted from medical records. RESULTS: One hundred fifty-eight women diagnosed (mean age, 24 years) underwent dilatation and curettage. Molar pregnancy was suspected at presentation in 111 (70%); 47 (30%) cases were presumed miscarriages, and the diagnosis was confirmed only after histologic evaluation of the specimen. Initial testing included complete blood count (CBC) (87%), liver function tests (LFT) (63%), thyroid-stimulating hormone (TSH) level (72%), clotting function studies (26%) and chest radiograph (84%). One patient with right upper quadrant pain had elevated LFTs and a coagulopathy that resolved after evacuation. One woman with a palpably enlarged goiter and elevated TSH level was diagnosed with thyroid carcinoma. No chest radiograph demonstrated metastatic disease. CONCLUSION: We advocate a simplified approach to preevacuation testing for suspected molar pregnancy that includes a CBC and blood type with antibody screen. Clinical assessment should prompt additional evaluation in the rare patient with suspicious signs and symptoms.

Original languageEnglish (US)
Pages (from-to)685-688
Number of pages4
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume52
Issue number8
StatePublished - Aug 2007

Fingerprint

Hydatidiform Mole
Blood Cell Count
Thyrotropin
Thorax
Dilatation and Curettage
Liver Function Tests
Goiter
Patient Rights
Spontaneous Abortion
Thyroid Neoplasms
Signs and Symptoms
Medical Records
Pain
Antibodies

Keywords

  • Gestational trophoblastic neoplasms
  • Gonadotropins
  • Hydatidiform mole

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Simplifying the preevacuation testing strategy for patients with molar pregnancy. / Knowles, Lynne M.; Drake, Richard D.; Ashfaq, Raheela; Castrillon, Diego H.; Miller, David S.; Schorge, John O.

In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist, Vol. 52, No. 8, 08.2007, p. 685-688.

Research output: Contribution to journalArticle

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