Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis

Pengda Liu, Wenjian Gan, Hiroyuki Inuzuka, Adam S. Lazorchak, Daming Gao, Omotooke Arojo, Dou Liu, Lixin Wan, Bo Zhai, Yonghao Yu, Min Yuan, Byeong Mo Kim, Shavali Shaik, Suchithra Menon, Steven P. Gygi, Tae Ho Lee, John M. Asara, Brendan D. Manning, John Blenis, Bing SuWenyi Wei

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Medicine & Life Sciences