Single-dose breath-hold gadolinium-enhanced three-dimensional MR angiography of the renal arteries

Vivian S. Lee, Neil M. Rofsky, Glenn A. Krinsky, David H. Stemerman, Jeffrey C. Weinreb

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

PURPOSE: To evaluate the quality of single-dose breath-hold three- dimensional (3D) magnetic resonance (MR) angiography of the renal arteries optimized with a 1-mL test bolus timing examination. MATERIALS AND METHODS: Three-dimensional spoiled gradient-echo imaging (3.8-4.2/1.3-1.7 [repetition time msec/echo time msec], 25°-40°flip angle) was performed in 60 patients after administration of gadopentetate dimeglumine (average dose, 0.11 mmol/kg). Synchronization of contrast material administration with data acquisition was achieved with a 1-mL test dose of contrast material to estimate patient circulation parameters. Image quality was assessed by using contrast-to-noise (CNR), relative vascular enhancement, and venous-to- arterial enhancement ratios and subjective scoring of arterial and venous enhancement. The effect of the contrast material injection rate and the influence of breath holding during the timing examination also were examined. RESULTS: Overall, of 60 studies, 58 were diagnostic and 56 demonstrated excellent arterial enhancement. Venous enhancement was seen in eight studies. The average aortic relative vascular enhancement (± SD) was 14.6 ± 5.9, with an aorta-to-inferior vena cava (IVC) CNR of 69.7 ± 43.9. The IVC-to- aorta venous-to-arterial enhancement ratio averaged 0.08 ± 0.16. There was no significant difference in image quality based on injection rates or the performance of breath holding during the timing examination (P > .1). CONCLUSION: Breath-hold gadolinium-enhanced renal MR angiography free of venous enhancement can be performed consistently and reliably with 20 mL of contrast material when studies are synchronized to patient circulation time by using a timing examination.

Original languageEnglish (US)
Pages (from-to)69-78
Number of pages10
JournalRadiology
Volume211
Issue number1
StatePublished - 1999

Fingerprint

Magnetic Resonance Angiography
Gadolinium
Renal Artery
Contrast Media
Breath Holding
Inferior Vena Cava
Blood Vessels
Aorta
Noise
Gadolinium DTPA
Injections
Kidney

Keywords

  • Gadolinium
  • Kidney, diseases
  • Magnetic resonance (MR), angiography
  • Magnetic resonance (MR), pulse sequences
  • Magnetic resonance, contrast agents

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Lee, V. S., Rofsky, N. M., Krinsky, G. A., Stemerman, D. H., & Weinreb, J. C. (1999). Single-dose breath-hold gadolinium-enhanced three-dimensional MR angiography of the renal arteries. Radiology, 211(1), 69-78.

Single-dose breath-hold gadolinium-enhanced three-dimensional MR angiography of the renal arteries. / Lee, Vivian S.; Rofsky, Neil M.; Krinsky, Glenn A.; Stemerman, David H.; Weinreb, Jeffrey C.

In: Radiology, Vol. 211, No. 1, 1999, p. 69-78.

Research output: Contribution to journalArticle

Lee, VS, Rofsky, NM, Krinsky, GA, Stemerman, DH & Weinreb, JC 1999, 'Single-dose breath-hold gadolinium-enhanced three-dimensional MR angiography of the renal arteries', Radiology, vol. 211, no. 1, pp. 69-78.
Lee, Vivian S. ; Rofsky, Neil M. ; Krinsky, Glenn A. ; Stemerman, David H. ; Weinreb, Jeffrey C. / Single-dose breath-hold gadolinium-enhanced three-dimensional MR angiography of the renal arteries. In: Radiology. 1999 ; Vol. 211, No. 1. pp. 69-78.
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N2 - PURPOSE: To evaluate the quality of single-dose breath-hold three- dimensional (3D) magnetic resonance (MR) angiography of the renal arteries optimized with a 1-mL test bolus timing examination. MATERIALS AND METHODS: Three-dimensional spoiled gradient-echo imaging (3.8-4.2/1.3-1.7 [repetition time msec/echo time msec], 25°-40°flip angle) was performed in 60 patients after administration of gadopentetate dimeglumine (average dose, 0.11 mmol/kg). Synchronization of contrast material administration with data acquisition was achieved with a 1-mL test dose of contrast material to estimate patient circulation parameters. Image quality was assessed by using contrast-to-noise (CNR), relative vascular enhancement, and venous-to- arterial enhancement ratios and subjective scoring of arterial and venous enhancement. The effect of the contrast material injection rate and the influence of breath holding during the timing examination also were examined. RESULTS: Overall, of 60 studies, 58 were diagnostic and 56 demonstrated excellent arterial enhancement. Venous enhancement was seen in eight studies. The average aortic relative vascular enhancement (± SD) was 14.6 ± 5.9, with an aorta-to-inferior vena cava (IVC) CNR of 69.7 ± 43.9. The IVC-to- aorta venous-to-arterial enhancement ratio averaged 0.08 ± 0.16. There was no significant difference in image quality based on injection rates or the performance of breath holding during the timing examination (P > .1). CONCLUSION: Breath-hold gadolinium-enhanced renal MR angiography free of venous enhancement can be performed consistently and reliably with 20 mL of contrast material when studies are synchronized to patient circulation time by using a timing examination.

AB - PURPOSE: To evaluate the quality of single-dose breath-hold three- dimensional (3D) magnetic resonance (MR) angiography of the renal arteries optimized with a 1-mL test bolus timing examination. MATERIALS AND METHODS: Three-dimensional spoiled gradient-echo imaging (3.8-4.2/1.3-1.7 [repetition time msec/echo time msec], 25°-40°flip angle) was performed in 60 patients after administration of gadopentetate dimeglumine (average dose, 0.11 mmol/kg). Synchronization of contrast material administration with data acquisition was achieved with a 1-mL test dose of contrast material to estimate patient circulation parameters. Image quality was assessed by using contrast-to-noise (CNR), relative vascular enhancement, and venous-to- arterial enhancement ratios and subjective scoring of arterial and venous enhancement. The effect of the contrast material injection rate and the influence of breath holding during the timing examination also were examined. RESULTS: Overall, of 60 studies, 58 were diagnostic and 56 demonstrated excellent arterial enhancement. Venous enhancement was seen in eight studies. The average aortic relative vascular enhancement (± SD) was 14.6 ± 5.9, with an aorta-to-inferior vena cava (IVC) CNR of 69.7 ± 43.9. The IVC-to- aorta venous-to-arterial enhancement ratio averaged 0.08 ± 0.16. There was no significant difference in image quality based on injection rates or the performance of breath holding during the timing examination (P > .1). CONCLUSION: Breath-hold gadolinium-enhanced renal MR angiography free of venous enhancement can be performed consistently and reliably with 20 mL of contrast material when studies are synchronized to patient circulation time by using a timing examination.

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