Single institution experience with tru-cut renal mass biopsy for diagnosing wilms tumor

Nicholas G. Cost, Candace F. Granberg, Bruce J Schlomer, Jonathan E Wickiser, Patricio C. Gargollo, Linda A Baker, Dinesh Rakheja

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Purpose: To evaluate the efficacy of needle biopsy for diagnosing Wilms tumor (WT) before chemotherapy. Materials and Methods: We reviewed our institutional experience with Tru-Cut biopsy of pediatnc renal masses in patients who subsequently underwent nephrectomy. We compared biopsy pathology with nephrectomy specimens to determine if biopsy accurately predicted final pathology. Results: Seven children underwent Tru-Cut renal mass biopsy followed by surgical resection. In 4 patients, the final biopsy pathology was definitively read as WT and in 3 subjects, the pathology was read as WT versus hyperplastic nephrogemc rest. In all 7 patients, the nephrectomy pathology confirmed a diagnosis of WT. There were no complications after biopsy, and no patients have had local or regional recurrence. Conclusion: In our experience, pre-therapy Tru-Cut biopsy safely provides an adequate specimen for pathologic review in diagnosing WT.

Original languageEnglish (US)
Pages (from-to)780-783
Number of pages4
JournalUrology Journal
Volume10
Issue number1
StatePublished - May 7 2013

Keywords

  • Diagnosis
  • Kidney neoplasms
  • Nephroblastoma
  • Pediatrics
  • Wilms tumor

ASJC Scopus subject areas

  • Urology

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