Sjögren's syndrome

Diagnosis and management

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

This article reviews current understanding of the clinical manifestations, diagnosis and treatment of Sjögren's syndrome. Sjögren's syndrome is a chronic inflammatory disorder of the exocrine glands with multiple nonexocrine features. It is found predominantly in middle-aged women but exists throughout the population. The diagnosis of Sjögren's syndrome can be challenging because the cardinal sicca symptoms may be subclinical or attributed to other causes, such as medications or aging. Differential diagnosis of Sjögren's syndrome can be confounded by the multiple exocrine manifestations in the mouth, eyes, ears, nose, skin, vagina, and respiratory and gastrointestinal tracts, as well as seemingly unrelated nonexocrine involvement in the thyroid, liver, kidneys and the musculoskeletal, vascular and nervous systems. This article concludes that early diagnosis of Sjögren's syndrome is crucial to prevent and/or minimize potentially life-threatening complications. Periodic follow-up of patients' status and collaboration between the primary-care physician and the rheumatologist, dentist, ophthalmologist and other specialists are indispensable.

Original languageEnglish (US)
Pages (from-to)107-122
Number of pages16
JournalWomen's Health
Volume3
Issue number1
DOIs
StatePublished - Jan 1 2007

Fingerprint

Exocrine Glands
Musculoskeletal System
Primary Care Physicians
Vagina
Dentists
Nose
Respiratory System
Nervous System
Ear
Blood Vessels
Mouth
Gastrointestinal Tract
Early Diagnosis
Thyroid Gland
Differential Diagnosis
Kidney
Skin
Liver
Population
Therapeutics

Keywords

  • Autoimmune disease
  • Cevimeline
  • Diagnosis
  • Exocrinopathy
  • Multisystem disorder
  • Pilocarpine
  • Salagen
  • Salivary substitute
  • Sjögren's syndrome
  • Treatment

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sjögren's syndrome : Diagnosis and management. / Al-Hashimi, Ibtisam.

In: Women's Health, Vol. 3, No. 1, 01.01.2007, p. 107-122.

Research output: Contribution to journalReview article

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