Sleep EEG features of adolescents with major depression

Graham J. Emslie, A. John Rush, Warren A. Weinberg, Jeanne W. Rintelmann, Howard P. Roffwarg

Research output: Contribution to journalArticle

60 Scopus citations

Abstract

A substantial body of research in adults has established that certain sleep polysomnographic abnormalities are commonly found in depressed patients, including sleep continuity disturbances, reduced slow-wave sleep, shortened rapid eye movement (REM) latency and increased REM density. To date the findings in depressed adolescents are equivocal. Three consecutive nights of polysomnographic recordings were obtained in 31 hospitalized depressed adolescents and 17 age-matched normal controls. The depressed adolescents had a shorter REM latency, shorter sleep latency, more REM sleep, and less stage 3 nonREM (NREM) sleep. There was a trend for melancholic and suicidal patients to have a shorter REM latency.

Original languageEnglish (US)
Pages (from-to)573-581
Number of pages9
JournalBiological Psychiatry
Volume36
Issue number9
DOIs
StatePublished - Nov 1 1994

Keywords

  • Depression
  • adolescents
  • controls
  • inpatients
  • sleep EEG

ASJC Scopus subject areas

  • Biological Psychiatry

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    Emslie, G. J., Rush, A. J., Weinberg, W. A., Rintelmann, J. W., & Roffwarg, H. P. (1994). Sleep EEG features of adolescents with major depression. Biological Psychiatry, 36(9), 573-581. https://doi.org/10.1016/0006-3223(94)90067-1