Slit-lamp, confocal, and light microscopic findings of corneal siderosis

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

PURPOSE: To report the clinical, histopathologic, and confocal findings of corneal siderosis. METHODS: A 35-year-old man presented after a car battery explosion with diffuse left corneal anterior stromal pigment deposition and an intraocular metallic foreign body of the left iris. The corneal pigment was analyzed by confocal microscopy and a lamellar corneal biopsy. RESULTS: Confocal microscopy showed the pigment to be highly reflective material in the corneal stroma with greatest density anteriorly. Histologic examination revealed the pigment to be iron with a diagnosis consistent with corneal siderosis. CONCLUSIONS: Corneal biopsy with Prussian blue established siderosis as the etiology of corneal pigmentation. A short delay in the removal of the foreign body contributed to the development of siderosis. The location of the foreign body on the iris may account for the predominant corneal involvement and relative sparing of the retina. Confocal microscopy may be useful in the evaluation of corneal siderosis.

Original languageEnglish (US)
Pages (from-to)1270-1272
Number of pages3
JournalCornea
Volume26
Issue number10
DOIs
StatePublished - Dec 2007

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Siderosis
Light
Foreign Bodies
Confocal Microscopy
Iris
Corneal Stroma
Biopsy
Explosions
Pigmentation
Retina
Iron
Slit Lamp

Keywords

  • Confocal microscopy
  • Cornea
  • Iron
  • Siderosis
  • Stromal pigment

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Slit-lamp, confocal, and light microscopic findings of corneal siderosis. / Witherspoon, S. Robert; Hogan, Robert N; Petroll, Walter M; Mootha, Venkateswara.

In: Cornea, Vol. 26, No. 10, 12.2007, p. 1270-1272.

Research output: Contribution to journalArticle

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abstract = "PURPOSE: To report the clinical, histopathologic, and confocal findings of corneal siderosis. METHODS: A 35-year-old man presented after a car battery explosion with diffuse left corneal anterior stromal pigment deposition and an intraocular metallic foreign body of the left iris. The corneal pigment was analyzed by confocal microscopy and a lamellar corneal biopsy. RESULTS: Confocal microscopy showed the pigment to be highly reflective material in the corneal stroma with greatest density anteriorly. Histologic examination revealed the pigment to be iron with a diagnosis consistent with corneal siderosis. CONCLUSIONS: Corneal biopsy with Prussian blue established siderosis as the etiology of corneal pigmentation. A short delay in the removal of the foreign body contributed to the development of siderosis. The location of the foreign body on the iris may account for the predominant corneal involvement and relative sparing of the retina. Confocal microscopy may be useful in the evaluation of corneal siderosis.",
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AU - Hogan, Robert N

AU - Petroll, Walter M

AU - Mootha, Venkateswara

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N2 - PURPOSE: To report the clinical, histopathologic, and confocal findings of corneal siderosis. METHODS: A 35-year-old man presented after a car battery explosion with diffuse left corneal anterior stromal pigment deposition and an intraocular metallic foreign body of the left iris. The corneal pigment was analyzed by confocal microscopy and a lamellar corneal biopsy. RESULTS: Confocal microscopy showed the pigment to be highly reflective material in the corneal stroma with greatest density anteriorly. Histologic examination revealed the pigment to be iron with a diagnosis consistent with corneal siderosis. CONCLUSIONS: Corneal biopsy with Prussian blue established siderosis as the etiology of corneal pigmentation. A short delay in the removal of the foreign body contributed to the development of siderosis. The location of the foreign body on the iris may account for the predominant corneal involvement and relative sparing of the retina. Confocal microscopy may be useful in the evaluation of corneal siderosis.

AB - PURPOSE: To report the clinical, histopathologic, and confocal findings of corneal siderosis. METHODS: A 35-year-old man presented after a car battery explosion with diffuse left corneal anterior stromal pigment deposition and an intraocular metallic foreign body of the left iris. The corneal pigment was analyzed by confocal microscopy and a lamellar corneal biopsy. RESULTS: Confocal microscopy showed the pigment to be highly reflective material in the corneal stroma with greatest density anteriorly. Histologic examination revealed the pigment to be iron with a diagnosis consistent with corneal siderosis. CONCLUSIONS: Corneal biopsy with Prussian blue established siderosis as the etiology of corneal pigmentation. A short delay in the removal of the foreign body contributed to the development of siderosis. The location of the foreign body on the iris may account for the predominant corneal involvement and relative sparing of the retina. Confocal microscopy may be useful in the evaluation of corneal siderosis.

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KW - Stromal pigment

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