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Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors
Chase H. Melick,
Jenna L. Jewell
ML-Lab Jewell
Molecular Biology
Research output
:
Contribution to journal
›
Article
›
peer-review
8
Scopus citations
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Medicine & Life Sciences
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide
78%
TOR Serine-Threonine Kinases
64%
Phosphorylation
39%
Phosphotransferases
31%
Sirolimus
17%
Adenosine Triphosphate
12%
Mechanistic Target of Rapamycin Complex 2
11%
Mechanistic Target of Rapamycin Complex 1
10%
Phosphoric Monoester Hydrolases
8%
Biological Products
8%
Names
7%
Nutrients
7%
Pharmacology
5%
Cell Line
4%
Growth
4%
Pharmaceutical Preparations
3%
Therapeutics
1%
Chemical Compounds
Mammalian Target of Rapamycin Inhibitor
100%
Thr-Ser
20%
Molecule
19%
Phosphotransferase Inhibitor
18%
Dephosphorylation
18%
Nutrient
15%
Occurrence in Nature
11%
Ethyl
10%
Drug
7%