SmI2 mediated reductive addition of bis-phenylsulfones to ketones

S. Chandrasekhar, Jurong Yu, J R Falck, C. Mioskowski

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

SmI2 mediates the in situ reductive addition of geminal bis-phenylsulfones to unhindered ketones at room temperature affording β-hydroxyphenylsulfones in good to excellent yields.

Original languageEnglish (US)
Pages (from-to)5441-5444
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number30
DOIs
StatePublished - Jul 25 1994

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Ketones
Temperature

Keywords

  • alkylation
  • desulfonylation
  • diiodosamarium
  • β-hydroxyphenylsulfone

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

SmI2 mediated reductive addition of bis-phenylsulfones to ketones. / Chandrasekhar, S.; Yu, Jurong; Falck, J R; Mioskowski, C.

In: Tetrahedron Letters, Vol. 35, No. 30, 25.07.1994, p. 5441-5444.

Research output: Contribution to journalArticle

Chandrasekhar, S. ; Yu, Jurong ; Falck, J R ; Mioskowski, C. / SmI2 mediated reductive addition of bis-phenylsulfones to ketones. In: Tetrahedron Letters. 1994 ; Vol. 35, No. 30. pp. 5441-5444.
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