Software for analyzing the behavioural test "morris Water Maze"

Arseny Zorin, Daria Chernyuk, Olga Vlasova, Marina Bolsunovskaya, Ilya Bezprozvanny

Research output: Contribution to journalConference articlepeer-review

Abstract

The Morris Water Maze Behavioural Test is a universal method for testing cognitive functions in experimental rodents, and it is especially effective in detecting deviations in memory functions and learning, which makes it indispensable in the study of neurodegenerative diseases, effect of therapeutic drugs, rodent stroke and aging models etc. However, despite the wide range of possible applications, data analysis makes the use of this test difficult. Currently, automated tracking and analysis programs of rodent moving are becoming to be popular. Thus, our goal was to develop and create an available quality product, which will allow the scientist to carry out research as efficiently as possible doing various options of the "Morris water maze"using latest modern parameters. In this article, we analyze different types of the Morris water maze methodology and the current scientific parameters of this test to understand the necessary and optimal capabilities of the future program, then to overcome the limitations of the systems currently available we have combined detection and tracking techniques into one standalone tool. The result of the work is a software product that allows to quickly and accurately detect the trajectory of animal moving in the water, and also provides parameters for evaluating the cognitive functions of memory and learning.

Original languageEnglish (US)
Article number01029
JournalE3S Web of Conferences
Volume203
DOIs
StatePublished - Nov 5 2020
Event2020 Ecological and Biological Well-Being of Flora and Fauna, EBWFF 2020 - Blagoveshchensk, Russian Federation
Duration: Sep 23 2020Sep 24 2020

ASJC Scopus subject areas

  • Environmental Science(all)
  • Energy(all)
  • Earth and Planetary Sciences(all)

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