Southwestern Internal Medicine Conference: Medical management of nephrolithiasis - A new, simplified approach for general practice

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24 Citations (Scopus)

Abstract

Considerable progress has been made regarding pathophysiology, diagnosis, and medical prevention of recurrent renal stone formation. The medical approach is not applied widely because of the availability of extracorporeal shockwave lithotripsy and the complexity of medical diagnostic and treatment modalities. In this review, a simplified program for the medical management of stones is described. From analysis of stone risk factors in 24-hour urine specimens, uncomplicated calcium stone disease is separated from other stone diseases. The uncomplicated calcium stone disease, comprising the illness in the majority of patients with recurrent renal calculi, is characterized by normocalcemia, normouricemia, calcium stones, and the absence of urinary tract infection, bowel disease, or marked hyperoxaluria. Uncomplicated calcium stone disease is separated into a hypercalciuric group and a normocalciuric group. In the simplified treatment program, the hyper-calciuric group would be offered thiazide plus potassium citrate, whereas the normocalciuric group would receive potassium citrate alone.

Original languageEnglish (US)
Pages (from-to)215-219
Number of pages5
JournalAmerican Journal of the Medical Sciences
Volume313
Issue number4
DOIs
StatePublished - 1997

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Nephrolithiasis
Internal Medicine
General Practice
Potassium Citrate
Calcium
Hyperoxaluria
Thiazides
Kidney Calculi
Lithotripsy
Urinary Tract Infections
Urine
Kidney
Therapeutics

Keywords

  • Medical management
  • Nephrolithiasis
  • Simplified treatment

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "Considerable progress has been made regarding pathophysiology, diagnosis, and medical prevention of recurrent renal stone formation. The medical approach is not applied widely because of the availability of extracorporeal shockwave lithotripsy and the complexity of medical diagnostic and treatment modalities. In this review, a simplified program for the medical management of stones is described. From analysis of stone risk factors in 24-hour urine specimens, uncomplicated calcium stone disease is separated from other stone diseases. The uncomplicated calcium stone disease, comprising the illness in the majority of patients with recurrent renal calculi, is characterized by normocalcemia, normouricemia, calcium stones, and the absence of urinary tract infection, bowel disease, or marked hyperoxaluria. Uncomplicated calcium stone disease is separated into a hypercalciuric group and a normocalciuric group. In the simplified treatment program, the hyper-calciuric group would be offered thiazide plus potassium citrate, whereas the normocalciuric group would receive potassium citrate alone.",
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