Spastin joins LDs and peroxisomes in the interorganelle contact ballet

Research output: Contribution to journalComment/debate

Abstract

Lipid droplets (LDs) store energy-rich fatty acids (FAs), but to harvest them, LDs donate FAs to peroxisomes for oxidation. In this issue, Chang et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902061) identify M1 Spastin as an LD-peroxisome tether that interacts with ESCRT-III components to facilitate lipid exchange between these two organelles.

Original languageEnglish (US)
Pages (from-to)2439-2441
Number of pages3
JournalThe Journal of cell biology
Volume218
Issue number8
DOIs
StatePublished - Aug 5 2019

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Peroxisomes
Fatty Acids
Endosomal Sorting Complexes Required for Transport
Organelles
Lipids
Lipid Droplets

ASJC Scopus subject areas

  • Cell Biology

Cite this

Spastin joins LDs and peroxisomes in the interorganelle contact ballet. / Henne, William M.

In: The Journal of cell biology, Vol. 218, No. 8, 05.08.2019, p. 2439-2441.

Research output: Contribution to journalComment/debate

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