Abstract
Foreign DNA activates the innate immune response through Toll-like receptor 9 (TLR9). In this issue of Immunity, Park et al. (2011) present evidence that granulin is a cofactor for TLR9 activation, delivering CpG-oligodeoxynucleotides to TLR9 in endolysosomes.
Original language | English (US) |
---|---|
Pages (from-to) | 453-455 |
Number of pages | 3 |
Journal | Immunity |
Volume | 34 |
Issue number | 4 |
DOIs | |
State | Published - Apr 22 2011 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Infectious Diseases