Specific degradation of keratin in Xenopus laevis egg extracts undergoing apoptosis

S. Zhu; Z. Lu; Y. Sun; Z. Zhai

doi:10.1007/BF02909691

Specific degradation of keratin in Xenopus laevis egg extracts undergoing apoptosis

S. Zhu, Z. Lu, Y. Sun, Z. Zhai

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Cytochrome c activates apoptosis specific protease XCPP32 when being added to Xenopus laevis egg extracts, and induces apoptosis in this cell-free system. During apoptosis, cyto-skeleton proteins in egg extracts are degraded. Western blot assay indicates that 42-ku acidic keratin in egg extracts has been degraded by XCPP32. The degradation of 42-ku keratin may be crucial in apoptosis.

Original language	English (US)
Pages (from-to)	1977-1981
Number of pages	5
Journal	Chinese Science Bulletin
Volume	45
Issue number	21
DOIs	https://doi.org/10.1007/BF02909691
State	Published - 2000

Keywords

Apoptosis
Cytochrome c
Keratin
XCPP32
Xenopus laevis egg extracts

ASJC Scopus subject areas

General

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10.1007/BF02909691

Cite this

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title = "Specific degradation of keratin in Xenopus laevis egg extracts undergoing apoptosis",

abstract = "Cytochrome c activates apoptosis specific protease XCPP32 when being added to Xenopus laevis egg extracts, and induces apoptosis in this cell-free system. During apoptosis, cyto-skeleton proteins in egg extracts are degraded. Western blot assay indicates that 42-ku acidic keratin in egg extracts has been degraded by XCPP32. The degradation of 42-ku keratin may be crucial in apoptosis.",

keywords = "Apoptosis, Cytochrome c, Keratin, XCPP32, Xenopus laevis egg extracts",

author = "S. Zhu and Z. Lu and Y. Sun and Z. Zhai",

year = "2000",

doi = "10.1007/BF02909691",

language = "English (US)",

volume = "45",

pages = "1977--1981",

journal = "Chinese Science Bulletin",

issn = "1001-6538",

publisher = "Springer Science + Business Media",

number = "21",

}

TY - JOUR

T1 - Specific degradation of keratin in Xenopus laevis egg extracts undergoing apoptosis

AU - Zhu, S.

AU - Lu, Z.

AU - Sun, Y.

AU - Zhai, Z.

PY - 2000

Y1 - 2000

N2 - Cytochrome c activates apoptosis specific protease XCPP32 when being added to Xenopus laevis egg extracts, and induces apoptosis in this cell-free system. During apoptosis, cyto-skeleton proteins in egg extracts are degraded. Western blot assay indicates that 42-ku acidic keratin in egg extracts has been degraded by XCPP32. The degradation of 42-ku keratin may be crucial in apoptosis.

AB - Cytochrome c activates apoptosis specific protease XCPP32 when being added to Xenopus laevis egg extracts, and induces apoptosis in this cell-free system. During apoptosis, cyto-skeleton proteins in egg extracts are degraded. Western blot assay indicates that 42-ku acidic keratin in egg extracts has been degraded by XCPP32. The degradation of 42-ku keratin may be crucial in apoptosis.

KW - Apoptosis

KW - Cytochrome c

KW - Keratin

KW - XCPP32

KW - Xenopus laevis egg extracts

UR - http://www.scopus.com/inward/record.url?scp=0034485092&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034485092&partnerID=8YFLogxK

U2 - 10.1007/BF02909691

DO - 10.1007/BF02909691

M3 - Article

AN - SCOPUS:0034485092

SN - 1001-6538

VL - 45

SP - 1977

EP - 1981

JO - Chinese Science Bulletin

JF - Chinese Science Bulletin

IS - 21

ER -

Specific degradation of keratin in Xenopus laevis egg extracts undergoing apoptosis

Abstract

Keywords

ASJC Scopus subject areas

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