SPECT electronic collimation resolution enhancement using chi-square minimization

J. W. Durkee, P. P. Antich, E. N. Tsyganov, A. Constantinescu, J. L. Fernando, P. V. Kulkarni, B. J. Smith, G. M. Arbique, M. A. Lewis, T. Nguyen, A. Raheja, G. Thambi, R. W. Parkey

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

An electronic collimation technique is developed which utilizes the chi- square goodness-of-fit measure to filter scattered gammas incident upon a medical imaging detector. In this data mining technique, Compton kinematic expressions are used as the chi-square fitting templates for measured energy- deposition data involving multiple-interaction scatter sequences. Fit optimization is conducted using the Davidon variable metric minimization algorithm to simultaneously determine the best-fit gamma scatter angles and their associated uncertainties, with the uncertainty associated with the first scatter angle corresponding to the angular resolution precision for the source. The methodology requires no knowledge of materials and geometry. This pattern recognition application enhances the ability to select those gammas that will provide the best resolution for input to reconstruction software. Illustrative computational results are presented for a conceptual truncated- ellipsoid polystyrene position-sensitive fibre head-detector Monte Carlo model using a triple Compton scatter gamma sequence assessment for a 99mTc point source. A filtration rate of 94.3% is obtained, resulting in an estimated sensitivity approximately three orders of magnitude greater than a high-resolution mechanically collimated device. The technique improves the nominal single-scatter angular resolution by up to approximately 24 per cent as compared with the conventional analytic electronic collimation measure.

Original languageEnglish (US)
Pages (from-to)2949-2974
Number of pages26
JournalPhysics in Medicine and Biology
Volume43
Issue number10
DOIs
StatePublished - Oct 1998

Fingerprint

collimation
angular resolution
Single-Photon Emission-Computed Tomography
Uncertainty
Detectors
goodness of fit
data mining
optimization
Data Mining
augmentation
Polystyrenes
detectors
Medical imaging
Diagnostic Imaging
ellipsoids
electronics
Biomechanical Phenomena
pattern recognition
point sources
Pattern recognition

ASJC Scopus subject areas

  • Biomedical Engineering
  • Physics and Astronomy (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Durkee, J. W., Antich, P. P., Tsyganov, E. N., Constantinescu, A., Fernando, J. L., Kulkarni, P. V., ... Parkey, R. W. (1998). SPECT electronic collimation resolution enhancement using chi-square minimization. Physics in Medicine and Biology, 43(10), 2949-2974. https://doi.org/10.1088/0031-9155/43/10/020

SPECT electronic collimation resolution enhancement using chi-square minimization. / Durkee, J. W.; Antich, P. P.; Tsyganov, E. N.; Constantinescu, A.; Fernando, J. L.; Kulkarni, P. V.; Smith, B. J.; Arbique, G. M.; Lewis, M. A.; Nguyen, T.; Raheja, A.; Thambi, G.; Parkey, R. W.

In: Physics in Medicine and Biology, Vol. 43, No. 10, 10.1998, p. 2949-2974.

Research output: Contribution to journalArticle

Durkee, JW, Antich, PP, Tsyganov, EN, Constantinescu, A, Fernando, JL, Kulkarni, PV, Smith, BJ, Arbique, GM, Lewis, MA, Nguyen, T, Raheja, A, Thambi, G & Parkey, RW 1998, 'SPECT electronic collimation resolution enhancement using chi-square minimization', Physics in Medicine and Biology, vol. 43, no. 10, pp. 2949-2974. https://doi.org/10.1088/0031-9155/43/10/020
Durkee JW, Antich PP, Tsyganov EN, Constantinescu A, Fernando JL, Kulkarni PV et al. SPECT electronic collimation resolution enhancement using chi-square minimization. Physics in Medicine and Biology. 1998 Oct;43(10):2949-2974. https://doi.org/10.1088/0031-9155/43/10/020
Durkee, J. W. ; Antich, P. P. ; Tsyganov, E. N. ; Constantinescu, A. ; Fernando, J. L. ; Kulkarni, P. V. ; Smith, B. J. ; Arbique, G. M. ; Lewis, M. A. ; Nguyen, T. ; Raheja, A. ; Thambi, G. ; Parkey, R. W. / SPECT electronic collimation resolution enhancement using chi-square minimization. In: Physics in Medicine and Biology. 1998 ; Vol. 43, No. 10. pp. 2949-2974.
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