TY - JOUR
T1 - Spectrophotometric simultaneous determination of Zinc(II), manganese(II) and iron(II) in pharmaceutical preparations using OSC-PLS
AU - Niazi, Ali
AU - Yazdanipour, Azadeh
AU - Goodarzi, Mohammad
AU - Kamkar, Hamidreza
AU - Rafinejad, Ali
PY - 2006/10
Y1 - 2006/10
N2 - This work reports the spectrophotometric simultaneous determination of zinc(II), manganese(II) and iron(II) in pharmaceutical preparation, using orthogonal signal correction-partial least squares (OSC-PLS). All the factors affecting on the sensitivity were optimized and the linear dynamic range for determination of these metals was found. The PLS modeling was used for the multivariate calibration of the spectrophotometric data. The OSC was used for preprocessing of data matrices and the prediction results of model. The experimental calibration matrix was designed by measuring the absorbance over the range 450-570 nm for 21 samples of 0.05-1.05, 0.10-1.10 and 0.05-1.05 μg·mL-1 of zinc(II), manganese(II) and iron(II), respectively. The RMSEP for zinc(II), manganese(II) and iron(II) using OSC-PLS were 0.0164, 0.0132, 0.0146, respectively. The proposed method was successfully applied the determination of zinc(II), manganese(II) and iron(II) in pharmaceutical preparations.
AB - This work reports the spectrophotometric simultaneous determination of zinc(II), manganese(II) and iron(II) in pharmaceutical preparation, using orthogonal signal correction-partial least squares (OSC-PLS). All the factors affecting on the sensitivity were optimized and the linear dynamic range for determination of these metals was found. The PLS modeling was used for the multivariate calibration of the spectrophotometric data. The OSC was used for preprocessing of data matrices and the prediction results of model. The experimental calibration matrix was designed by measuring the absorbance over the range 450-570 nm for 21 samples of 0.05-1.05, 0.10-1.10 and 0.05-1.05 μg·mL-1 of zinc(II), manganese(II) and iron(II), respectively. The RMSEP for zinc(II), manganese(II) and iron(II) using OSC-PLS were 0.0164, 0.0132, 0.0146, respectively. The proposed method was successfully applied the determination of zinc(II), manganese(II) and iron(II) in pharmaceutical preparations.
KW - Iron(II)
KW - Manganese(II)
KW - OSC-PLS
KW - Pharmaceutical
KW - Spectrophotometric
KW - Zinc(II)
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M3 - Article
AN - SCOPUS:33751067564
SN - 1001-8417
VL - 17
SP - 1347
EP - 1350
JO - Chinese Chemical Letters
JF - Chinese Chemical Letters
IS - 10
ER -