Splenic Involvement in Disseminated Mycobacterium avium-intracellulare Infection

Magnetic Resonance Imaging Findings

Research output: Contribution to journalArticle

Abstract

ABSTRACT: We report the imaging findings of a patient with disseminated Mycobacterium avium-intracellulare complex presenting with multiple splenic lesions incompletely characterized on computed tomography in whom magnetic resonance imaging helped narrow the differential diagnosis. We discuss the magnetic resonance imaging findings suggesting the diagnosis, including the presence of focal susceptibility artifact within the lesions (ie, signal drop on T1 in-phase imaging), marked hypointensity on diffusion-weighted imaging, and faint progressive peripheral enhancement after contrast administration. We provide pathologic correlation to explain these imaging characteristics and a review of the literature of imaging characteristics in splenic involvement of M. avium-intracellulare complex infection.

Original languageEnglish (US)
JournalJournal of Computer Assisted Tomography
DOIs
StateAccepted/In press - Jul 13 2017

Fingerprint

Mycobacterium avium-intracellulare Infection
Mycobacterium avium Complex
Magnetic Resonance Imaging
Artifacts
Differential Diagnosis
Tomography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

@article{b339444816df4391b5363e67e0d4e5d7,
title = "Splenic Involvement in Disseminated Mycobacterium avium-intracellulare Infection: Magnetic Resonance Imaging Findings",
abstract = "ABSTRACT: We report the imaging findings of a patient with disseminated Mycobacterium avium-intracellulare complex presenting with multiple splenic lesions incompletely characterized on computed tomography in whom magnetic resonance imaging helped narrow the differential diagnosis. We discuss the magnetic resonance imaging findings suggesting the diagnosis, including the presence of focal susceptibility artifact within the lesions (ie, signal drop on T1 in-phase imaging), marked hypointensity on diffusion-weighted imaging, and faint progressive peripheral enhancement after contrast administration. We provide pathologic correlation to explain these imaging characteristics and a review of the literature of imaging characteristics in splenic involvement of M. avium-intracellulare complex infection.",
author = "Haley Clark and Gaurav Khatri and Payal Kapur and Ivan Pedrosa",
year = "2017",
month = "7",
day = "13",
doi = "10.1097/RCT.0000000000000639",
language = "English (US)",
journal = "Journal of Computer Assisted Tomography",
issn = "0363-8715",
publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Splenic Involvement in Disseminated Mycobacterium avium-intracellulare Infection

T2 - Magnetic Resonance Imaging Findings

AU - Clark, Haley

AU - Khatri, Gaurav

AU - Kapur, Payal

AU - Pedrosa, Ivan

PY - 2017/7/13

Y1 - 2017/7/13

N2 - ABSTRACT: We report the imaging findings of a patient with disseminated Mycobacterium avium-intracellulare complex presenting with multiple splenic lesions incompletely characterized on computed tomography in whom magnetic resonance imaging helped narrow the differential diagnosis. We discuss the magnetic resonance imaging findings suggesting the diagnosis, including the presence of focal susceptibility artifact within the lesions (ie, signal drop on T1 in-phase imaging), marked hypointensity on diffusion-weighted imaging, and faint progressive peripheral enhancement after contrast administration. We provide pathologic correlation to explain these imaging characteristics and a review of the literature of imaging characteristics in splenic involvement of M. avium-intracellulare complex infection.

AB - ABSTRACT: We report the imaging findings of a patient with disseminated Mycobacterium avium-intracellulare complex presenting with multiple splenic lesions incompletely characterized on computed tomography in whom magnetic resonance imaging helped narrow the differential diagnosis. We discuss the magnetic resonance imaging findings suggesting the diagnosis, including the presence of focal susceptibility artifact within the lesions (ie, signal drop on T1 in-phase imaging), marked hypointensity on diffusion-weighted imaging, and faint progressive peripheral enhancement after contrast administration. We provide pathologic correlation to explain these imaging characteristics and a review of the literature of imaging characteristics in splenic involvement of M. avium-intracellulare complex infection.

UR - http://www.scopus.com/inward/record.url?scp=85023748767&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85023748767&partnerID=8YFLogxK

U2 - 10.1097/RCT.0000000000000639

DO - 10.1097/RCT.0000000000000639

M3 - Article

JO - Journal of Computer Assisted Tomography

JF - Journal of Computer Assisted Tomography

SN - 0363-8715

ER -