Spontaneous interictal spiking in the awake kindled rat

J. G. Fitz, J. O. McNamara

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

The spontaneous interictal spike (SIS) noted in EEG recordings is a signal of the abnormally excitable behavior of neurons in an epileptic focus. This study provides a detailed, quantitative, temporal and spatial profile of SIS in the amygdaloid kindled rat. The reproducible nature of the development and decline of SIS in kindling provides a useful model for biochemical study of the mechanisms that initiate and regulate SIS.

Original languageEnglish (US)
Pages (from-to)592-596
Number of pages5
JournalElectroencephalography and Clinical Neurophysiology
Volume47
Issue number5
DOIs
StatePublished - Nov 1979

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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