ST segment resolution as a tool for assessing the efficacy of reperfusion therapy

James A de Lemos, Eugene Braunwald

Research output: Contribution to journalArticle

230 Citations (Scopus)

Abstract

Rapid, simple and inexpensive measures are needed to assess the efficacy of reperfusion therapy both in clinical practice and in clinical trials testing novel reperfusion regimens. In the last decade, several observations have led to a favorable reappraisal of the utility of ST segment monitoring as a simple means of assessing reperfusion in patients receiving fibrinolytic therapy for acute ST elevation myocardial infarction, and ST resolution is being used increasingly in clinical practice and in clinical research. This review focuses on four interrelated roles for ST segment monitoring: the assessment of epicardial reperfusion and the identification of candidates for rescue percutaneous coronary intervention; the evaluation of microvascular and tissue-level reperfusion; the determination of prognosis early after fibrinolytic therapy; and the use of ST segment resolution to compare different reperfusion regimens.

Original languageEnglish (US)
Pages (from-to)1283-1294
Number of pages12
JournalJournal of the American College of Cardiology
Volume38
Issue number5
DOIs
StatePublished - Nov 1 2001

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Reperfusion
Thrombolytic Therapy
Therapeutics
Percutaneous Coronary Intervention
Clinical Trials
Research

ASJC Scopus subject areas

  • Nursing(all)

Cite this

ST segment resolution as a tool for assessing the efficacy of reperfusion therapy. / de Lemos, James A; Braunwald, Eugene.

In: Journal of the American College of Cardiology, Vol. 38, No. 5, 01.11.2001, p. 1283-1294.

Research output: Contribution to journalArticle

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