Staphylococcus aureus with reduced susceptibility to vancomycin

S. E. Cosgrove, K. C. Carroll, T. M. Perl

Research output: Contribution to journalReview article

111 Scopus citations

Abstract

Infections with Staphylococcus aureus with reduced susceptibility to vancomycin continue to be reported, including 2 cases caused by S. aureus isolates with full resistance to vancomycin. This review first outlines the definitions of vancomycin-intermediate S. aureus (VISA) and vancomycin-resistant S. aureus (VRSA) and risk factors for infection. Next, we describe the mechanisms of resistance and methods of laboratory detection of the organisms. Finally, we address infection control and management issues associated with isolation of VISA and VRSA.

Original languageEnglish (US)
Pages (from-to)539-545
Number of pages7
JournalClinical Infectious Diseases
Volume39
Issue number4
DOIs
Publication statusPublished - Aug 15 2004

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ASJC Scopus subject areas

  • Immunology

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