Statins: Practical considerations - A review

Kazeen Abdullah, Anand Rohatgi

Research output: Contribution to journalReview article

Abstract

Statins are currently the most efficacious and widely prescribed lipid-lowering medications. The 2013 ACC/AHA cholesterol guidelines provide a dramatic shift in treatment approach with a focus on fixed-dose statins matched to individual risk scores. Statin intolerance is not uncommon and can be challenging to diagnose and manage; however, several therapeutic strategies have been successful in achieving statin tolerance. Statin use is also associated with liver enzyme elevations and increased risk of incident diabetes, but studies show these individuals benefit from statins. Several guidelines exist and statin use is expected to increase with the new cholesterol guidelines bringing along new challenges for prescribers. This review article will provide practical considerations for statin use and management of statin intolerance.

Original languageEnglish (US)
Pages (from-to)71-75
Number of pages5
JournalEuropean Cardiology Review
Volume9
Issue number2
DOIs
StatePublished - Jan 1 2014

Keywords

  • ASCVD
  • CKD
  • Cholesterol
  • Considerations
  • Diabetes
  • Guidelines
  • Intolerance
  • Practical
  • Review
  • Statin

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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